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ISSN: 2329-6925
Journal of Vascular Medicine & Surgery
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Bilateral Radial Artery Aneurysm: Case Report and Review of Literature

Thai H*, Vasyluk A and Rits Y

Vascular Surgery Fellow, Wayne State University SOM, Detroit Medical Center, USA

*Corresponding Author:
Thai H
Vascular Surgery Fellow
Wayne State University SOM
Detroit Medical Center, USA
Tel: 206-484-3664
E-mail: [email protected]

Received Date: June 10, 2015; Accepted Date: January 21, 2016; Published Date: January 29, 2016

Citation: Thai H, Vasyluk A, Rits Y (2016) Bilateral Radial Artery Aneurysm: Case Report and Review of Literature. J Vasc Med Surg 4:247. doi: 10.4172/2329-6925.1000247

Copyright: © 2016 Thai H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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While arterial aneurysm in the lower extremities is common, upper extremity aneurysms are relatively infrequent. Radial artery aneurysms are sometimes associated with trauma and connective tissue disorders. Very few cases of radial artery aneurysm have been reported in the literature. We have encountered a case of bilateral radial artery aneurysms in a 61 year old male. A review of the English language literature was performed using Pub Med database, resulting in 31 reported cases of radial artery aneurysms, with most cases being either traumatic or idiopathic in etiology. Of these reports, bilateral aneurysms had clear etiologies, including Marfan’s vasculopathy, granulomatous arteritis, arteriosclerotic disease and intra-arterial drug injection. To our knowledge, this is the first reported case of primary bilateral radial artery aneurysms.


Radial artery aneurysms; Peripheral aneurysms; Vasculitis

Case Report

A 61 year old left-hand dominant man with a history of frequent falls presented with bilateral hand pain and cellulitis. He has a history of falls in the weeks prior to presentation with redness, pain and swelling of his right wrist. Approximately a week later his left wrist and forearm also became swollen and erythematous. Physical exam revealed a moderately edematous left forearm with bilateral tender pulsatile masses at the wrists. Color flow duplex showed a maximum diameter of 1.3 and 1.5 cm of the left and right radial artery aneurysms, respectively, with intact palmar arches and bilateral radial dominance.

His past medical history includes hypertension and ischemic stroke two years ago. There was no indication from the history of connective tissue disease, and workup for vasculitis (sedimentation rate and C-reactive protein) was negative. A screening duplex of the popliteal arteries and CT of the chest and abdomen did not reveal other aneurysms.

Due to the size of the aneurysms and persistent symptoms operative management was discussed and the patient was taken to the operating room for subsequent aneurysm resection. The larger and more symptomatic aneurysm (right) side was resected first. Intraoperative findings showed significant inflammatory reaction and scar tissue encasing the aneurysm wall. There was an excellent doppler signal in the palmar and digits with the radial artery clamped. Thus we chose not to perform a bypass. A month later the patient returned for the left radial aneurysm resection. This aneurysm had septation and significant intramural thrombus. There was a radial artery dependent palmar circulation thus an interposition graft was performed with a reversed great saphenous vein. Patient experienced a full and uncomplicated recovery. Histological examination of the right aneurysm revealed fibromyxoid degeneration of the media with elastic tissue degeneration, while the left specimen showed increased perivascular inflammatory infiltrate but was not conclusive for vasculitis.


True aneurysms of the radial artery are rare, with most reported being false aneurysms, traumatic or iatrogenic in origin. Given normal inflammatory markers and recent history of trauma, these aneurysms are likely secondary to trauma provoked. A search of Englishlanguage literature reveals 29 cases of true radial artery aneurysms, mostly reported as single cases or case series. Tables 1 and 2 of these 4 was bilateral [1-4]. The most commonly etiologies were idiopathic and traumatic aneurysms, although it has been suggested that some of the cases of unknown etiology may be due to unrecalled trauma [3]. Other less common etiologies included mycotic aneurysms [5,6] atherosclerosis [7], NF-1 vasculopathy [8,9], vasculitis [3], and Marfan’s syndrome [1,10]. The reported cases show a male predominance, with a mean age of 57 years, and most typically occur in the distal part of the artery, around the wrist and “snuffbox”, where the artery is most superficial.

Author Sex Gender Size/Location Etiology Treatment
Yukios [1] 74 Female 9 mm, 5 mm, snufbox (bilateral) Marfans Ligation + excision (right)
Malt [2] 56 Male 2.0 cm,1.5 cm, wrist (bilateral) Arteriosclerotic Resection +anastomosis (right)
Leitner [3] 69 Female 1.5 cm, 2.0 cm wrist (bilateral) Granulomatous arteritis Ligation + excision (bilateral)
Coppola [4] 40 Male Wrist (bilateral) Intrarterial drug injection Ligation + excision (bilateral)
Shaabi [13] 65 Female 2 × 1.5 cm snuffbox Idiopathic/non-traumatic Ligation + excision
Luzzani [19] 63 Female 1.0 ×  1.1 cm snuffbox Idiopathic/non-traumatic Ligation + excision
Yaghoubian [26] 77 Male 1.0 ×  1.5 cm distal to snuffbox Idiopathic/non-traumatic Observation
Claudio [18] 47 Female 1.1 ×  1.0 cm wrist Idiopathic/non-traumatic Ligation + excision
Walton [25] 40 Male 1.5 cm snuffbox Idiopathic/non-traumatic Observation
Turner [14] 55 Male 2.0 cm distal RA (antecubital fossa) Idiopathic/non-traumatic Resection + anastomosis
Filis [20] 45 Male 2.0 × 3.0 cm snuffbox Idiopathic/non-traumatic Ligation + excision
Jedynak [15] 60 Male Snuffbox Idiopathic/non-traumatic Ligation + excision
Lee [24] 42 Male Left wrist Idiopathic/non-traumatic Resection + anastomosis
Behar [21] 62 Male 1.9 cm wrist Repetitive trauma Ligation + excision
Turowski [11] 70 Female 2 cm ×  7 cm wrist Traumatic Reconstruction with interposition vein graft
Kadowaki [5] 61 Male 2.0 × 1.5 cm snuffbox Mycotic Ligation + excision
Singh [9] 45 Male  Proximal radial artery NF-1 vasculopathy Ligation (no excision)
De Santis [8] 48 Female Multiple proximal + distal aneurysms NF-1 vasculopathy Ligation + excision
Thorrens [7] 60 Male 1.5 × 2.0 cm snuffbox Ateriosclerotic Resection + anastomosis
Goertz[10] 52 Male Snuffbox Marfans Ligation + excision

Table 1: Size location/Etiology with multiple patients.

Author Number pts Location Etiology Management
Gray [12] 2 Distral radial artery/wrist 1.Repetitive trauma
2. Idiopathic
1.Ligation + excision
2. Observation
Johnson [6] 4 U/K Mycotic Ligation + excision
Mayall [22] 1(41M) Distal radial artery/wrist Trauma Ligation + excision
Ho [17] 1 Wrist Blunt trauma Reconstruction w/ vein graft
Igari [16] 1 (72F) Snuffbox Idiopathic Ligation + excision
Poirier[23] 1(69M) Wrist Mycotic Ligation + excision

Table 2: Case series/reports with multiple patients.

Most cases present as an asymptomatic swelling [2,7,11,12] but can present with paraesthesias due to radial nerve compression [13], symptoms of embolization [14] or rupture [8]. Diagnosis is often made on physical exam which shows a pulsatile mass, as well as non-invasive imaging such as doppler ultrasound. While most such aneurysms are traumatic or idiopathic in nature, efforts should be made to evaluate for vasculitis or connective tissue disease where appropriate, as well as screening for other aneurysms. Radial artery aneurysms are rare and its management is not well described. Early intervention is recommended to prevent distal embolization as well as addressing pain and compressive symptoms [15].

The most commonly reported approach for radial artery aneurysms is ligation and excision [5,12,13,16-23] which appears to be the preferred in cases where the ulnar artery is the dominant arterial supply for the hand [13,15]. In cases where the ulnar collaterals are poor or there is radial dominant circulation, options include excision and anastomosis [3,7,24] or excision with interposition vein graft [11,17] if a tension free anastomosis could not be accomplished, as in our case. A few reports exist of long term follow up for radial artery reconstruction, ranging from 3 months to 5 years follow up, with most reporting no complications, including growth or recurrence of the aneurysm, but there is one published report of re-occurrence of aneurysm at 18 months [17]. We recommend pre-operative evaluation of palmar circulation with a digital doppler ultrasound.

In summary we recommend radial aneurysms to be repaired due to risks of embolization in additional to pain and compressive symptoms [25,26]. Preoperative laboratory testing should include a SED rate and CRP to exclude inflammatory components. Evaluation of the palmar circulation is necessary for operative planning. Treatment can include simple ligation, excision with primary anastomosis or with an interposition graft.


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