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Can Nutraceuticals a Day Keep the Doctor Away?
ISSN: 2327-5162

Alternative & Integrative Medicine
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  • Editorial   
  • Altern Integr Med 2019, Vol 8(1): e122
  • DOI: 10.4172/2327-5162.1000e122

Can Nutraceuticals a Day Keep the Doctor Away?

Divya R1, Ashok V2 and Rajajeyakumar M3*
1Department of Physiology, Karpagam Faculty of Medical Sciences and Research, Chennai, India
2Department of Biochemistry, Karpagam Faculty of Medical Sciences and Research, Chennai, India
3Department of Physiology, Trichy SRM Medical College Hospital and Research Centre, Chennai, India
*Corresponding Author: Rajajeyakumar M, Department of Physiology, Trichy SRM Medical College Hospital and Research Centre, Chennai, India, Tel: 09751382650, Email: [email protected]

Received Date: Feb 11, 2019 / Accepted Date: Feb 13, 2019 / Published Date: Feb 18, 2019


'’So where do we go from here? Well, I think, again I'm not sure, that the quest to demonstrate whether chronic administration, long‐term diet, long‐term supplementation, can prevent serious diseases like cancer, heart disease, dementia, arthritis has come to an end’’. -Stephen L. DeFelice, 2014; said the man who lectured about the term ‘Nutraceutical’ in a scientific session 2014 [1]. The reputation of the Nutraceuticals and its evidence of efficiency is vague and every so often conflicting because of their meagre trial designs and inflated popularity for profitable drives [2,3].

Stephen DeFelice a renowned physician, the founder of ‘Foundation for Innovation in Medicine’ (FIM; Cranford, NJ, USA) coined the term 'Nutraceutical' in 1989 and defined Nutraceuticals as “a food or portion of a food substance that delivers health or medical benefits, which includes the treatment as well as the prevention of occurrence and progression of disease [4].

Various nutraceuticals tested or being tested

Nutraceutical Disease/Condition Tested Being tested
Soy protein (genistein) Coronary heart disease (reduces low-density lipoproteins) Yes
Omega-3 oil Coronary heart disease Yes
Black cohosh Menopausal hot flashes (serotonin modulation) Yes
Stanol/sterol esters Coronary heart disease (reduces low-density lipoproteins) Yes
Soy isoflavones Breast, prostate and bone cancer Yes
Phytoestrogens Cognition in post-menopausal women Yes
Cranberry Urinary tract infections Yes
Red clover Hormonal actions Yes
Chasteberry (vitex) Menstrual disorders Yes
Green tea Cancer Yes
Black haw (Virburnum prunifolium) Premenstrual tension Yes
Chinese mushrooms Prostate and bladder cancer Yes
Isothiocyanates Cancer Yes
Polyphenols Cancer Yes
Phytoestrogens Bone metabolism Yes
Lutein Macular degeneration Yes
Lycopene Cancer Yes

Table 1: List of various Nutraceuticals tested or being tested.

Source of Nutraceuticals

Commonly used Nutraceuticals are Curcumin which is extracted from the Indian spice turmeric, GAGs (Glucosamine Sulfate, Chondroitin Sulfate, and Hyaluronic Acid), ASU (Avocado/soy unsaponifiable (ASU) are plant extracts with a sterol-rich hydrolyzed lipid fraction that is extracted from soybean, avocado. Bioflavonoids,phytoflavonoids are polyphenols components that are extracted from vegetables and plants. Bromelain and ginger are obtained from immature fruits of pineapple and stems (Table 1).

Recently Nutraceutical interventions are used as a tactical means for prevention and management of geriatric diseases like osteoarthritis, Alzheimer’s because of its risk-benefit ratio, low cost. Furthermore, the recent research data reveals the fact that this kind of intervention ropes not only functional improvement, clinical symptoms, but also it helps in disease regression [5].


As we are in the era where the treatments are expensive and are incessantly increasing, the Nutraceuticals approaches have evolved as a novel, more effective and inexpensive intervention technique. The use of these agents can be increased by the appropriate formulations, improvised knowledge of selected Nutraceuticals with inclined bioavailability will certainly widen, the existing large group of population using the Nutraceuticals. Nevertheless, evidence-based data regarding the usage and its effects on the body systems is still deficient. More clinical trials are required to illuminate their role and ideal way and dosage administration are still needed to be studied.


Citation: Divya R, Ashok V, Rajajeyakumar M (2019) Can Nutraceuticals a Day Keep the Doctor Away?. Altern Integr Med 8: e122. DOI: 10.4172/2327-5162.1000e122

Copyright: © 2019 Divya R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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