Received date: September 25, 2016; Accepted date: September 28, 2016; Published date: September 30, 2016
Citation: Manso MA, Bermudez L, Orriach GJL, Núñez M, Hernandez P, et al. (2016) Clinical Image: Desflurane During Cardiopulmonary Bypass. J Cardiovasc Dis Diagn 4: i103. doi:10.4172/2329-9517.1000i103
Copyright: © 2016 Manso MA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Visit for more related articles at Journal of Cardiovascular Diseases & Diagnosis
There is growing evidence of the benefits of halogenated drugs compared to other hypnotics in patients undergoing cardiac surgery . Different trials have shown a protective effect on myocardial level, sevoflurane and desflurane being those who appear to have a greater advantage. At the same time studies show that continuous use of sevoflurane before, during and after cardiopulmonary bypass protects only if it is changed by another anesthetic at some point [2,3].
Desflurane has obvious advantages over other halogenated hydrocarbons, such as partition coefficient lower than allows decrease or increase the concentration in the target organ faster than with any other. However, it has been found that in patients undergoing cardiopulmonary bypass decreased concentration of desflurane in blood is less than that which occurs in a patient breathing normally , so that the change in hypnotic during by-pass cardiopulmonary could produce greater than necessary concentrations.
The uses of vaporizers that allow the use of desflurane during extracorporeal circulation keeps a single hypnotic throughout the process whose concentration can be changed quickly and in turn get all the benefits of myocardial protection of halogenated (Figure 1)..
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals