Received date: January 12, 2015; Accepted date: January 16, 2015; Published date: January 18, 2015
Citation: Keusch S (2015) Heterotopic Ossification after Lung Transplantation. J Pulm Respir Med 5:i011. doi: 10.4172/2161-105X.1000i011
Copyright: © 2015 Keusch S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Lung transplantation; Heterotopic ossification
A 40-year-old man who underwent lung transplantation for alpha-1-antitrypsine deficient emphysema showed in an abdominal x-ray, performed for the clinical suspicion of coprostasis, an unclear bone formation in the pelvis. He reported no complaints and clinical examination showed no tenderness, movement limitation or neurological deficits. In the computer tomography of the pelvis, surprisingly extraskeletal, heterotopic ossification of the gluteus minimus muscle of both sides were detected. No known risk factors for this pathology such as trauma, surgery, neurological or thermal injuries, or prolongued immobilization after transplantation could be established. It remains unclear if transplantation with start of triple immunosuppression or other unknown factors triggered this uncommon complication. In literature a case series (n=5) on heterotopic bone formation after transplantation (orthotopic liver and lung)  and a single case-report after lung transplantation  have been reported. Established treatment options are surgical excision or radiotherapy if symptoms are burdensome necessitating an intervention.