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Infiltrating Ductal Carcinoma T4b Classification - Medical Images
ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

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Infiltrating Ductal Carcinoma T4b Classification - Medical Images

David Gicheha Njoroge1,2*
1Pathology Department, The Karen Hospital, Nairobi, Kenya
2Cyto Hist Systems, East Africa, Nairobi, Kenya
*Corresponding Author: David Gicheha Njoroge, Pathology Department, The Karen Hospital, Nairobi, Kenya, Tel: +254206613000, Email: [email protected]

Received Date: Nov 23, 2017 / Accepted Date: Jan 08, 2018 / Published Date: Jan 17, 2018

Nonmetastatic non-inflammatory invasive breast cancers having skin involvement (SI) area unit classified as T4b, no matter size. This study evaluated malady specific survival (DSS) to work out whether or not size ought to be thought of for these lesions, instead of grouping all into Stage III [1,2].

Here we observed the Infiltrating ductal carcinoma T4b microscopic and Gross section. With microscopic section we observed infiltrating extremely organic phenomenon hyperchromatic cells with sac nuclei and distinguished nucleoliand lympho tube invasion. Nottingham combined microscopic anatomy score three with growth space forming cannular structures (40x; field diameter 0.50 mm. overall grade scores eight or nine. The invasive malignant neoplastic disease directly invades the corium with skin ulceration classified as T4B and also with Gross section. The skin show ulcer measuring 3 cm together with multiple whitish gray nodules affecting all quadrants (Figures 1 and 2).

cytology-histology-microscopy-pleomorphic-hyperchromatic

Figure 1: Microscopy - shows infiltrating highly pleomorphic hyperchromatic cells with vesicular nuclei and prominent nucleoli and lympho vascular invasion. Nottingham combined histological score 3 with tumour area forming tubular structures (40x; field diameter 0.50 mm. overall grade scores 8 or 9). The invasive carcinoma directly invades the dermis with skin ulceration classified as T4B.

cytology-histology-mastectomy-skin-ulcer

Figure 2: Gross - Total mastectomy specimen measuring 22 × 12 × 8 cm. The skin show ulcer measuring 3 cm together with multiple whitish gray nodules affecting all quadrants. The cut surface shows tumour area measuring 10 cm diameter.

References

Citation: Njoroge DG (2018) Infiltrating Ductal Carcinoma T4b Classification - Medical Images. J Cytol Histol 9: 498. DOI: 10.4172/2157-7099.1000498

Copyright: © 2018 Njoroge DG. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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