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Intracranial Leiomyosarcoma in an HIV-Infected Adult | OMICS International
ISSN: 2329-6895
Journal of Neurological Disorders
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Intracranial Leiomyosarcoma in an HIV-Infected Adult

Sombat Muengtaweepongsa1* and Punjama Lertbutsayanukul2
1Department of Medicine, Thammasat University, PathumThani, Thailand
2Department of Neuroradiology, Prasat Neurological Institute, Bangkok, Thailand
Corresponding Author : Sombat Muegtaweepongsa
Thammasat University, Rangsit Campus
Paholyothin Rd., Pathum
Thani,12120, Thailand
Tel: 666602613 3333
E-mail: [email protected]
Received November 02, 2014; Accepted November 04, 2014; Published November 06, 2014
Citation: Muengtaweepongsa S, Lertbutsayanukul P (2015) Intracranial Leiomyosarcoma in an HIV-Infected Adult. J Neurol Disord 3:i107. doi: 10.4172/2329-6895.1000i107
Copyright: © 2015 Muengtaweepongsa S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

This 33-year-old man presented with one-year history of intermittent left orbital pain and diplopia after was diagnosed as HIV infection for 6 months. He had limited movement of the left eye with impairment of nearly all gaze direction. RAPD was positive on the left. He had no weakness or sensory disturbance. MRI showed a well efined mass in the left cavernous sinus with post-gadolinium enhancement. Suprasellar extension with dural tail on the left side was noted with mild pressure effect to the left prechiasmatic optic nerve

Keywords
HIV; Leiomyosarcoma
Description
This 33-year-old man presented with one-year history of intermittent left orbital pain and diplopia after was diagnosed as HIV infection for 6 months. He had limited movement of the left eye with impairment of nearly all gaze direction. RAPD was positive on the left. He had no weakness or sensory disturbance. MRI showed a well efined mass in the left cavernous sinus with post-gadolinium enhancement. Suprasellar extension with dural tail on the left side was noted with mild pressure effect to the left prechiasmatic optic nerve (Figure 1). With the most likely preoperative diagnosis of intracavernous meningioma, the patient underwent craniotomy with partial tumor resection. The tumor appeared to be well-encapsulated and adhered to the intracavernous structure. The histopathologic study reported low-grade leiomyosarcoma (Figure 2). EBV is the postulated cause of this tumor [1]. Most of the leiomyosarcoma in HIV-infected patients was reported in children or young adults [2]. Leiomyosarcoma is considerable as a rare tumor in HIV-infected adults.
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