Institute of Experimental Pharmacology and Toxicology, The Slovak Academy of Sciences, Slovakia
Received Date: July 11, 2016; Accepted Date: July 13, 2016; Published Date: July 17, 2016
Citation: Durisova M (2016) Journal: Drug Metabolism Letters. J Drug Metab Toxicol 7:e134. doi: 10.4172/2157-7609.1000e134
Copyright: © 2016 Durisova M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Thematic issue proposal
Development of combined mathematical models for parent drugs and their metabolites is traditionally performed in the time domain. The goal of this proposal is to invite researchers in pharmacokinetics to the theory of dynamic systems and to use computational and modeling tools from the theory of dynamic systems for the development combined mathematical models for parent drugs and their metabolites.
Researchers interested may visit: https://www.omicsonline.org/openaccess/mathematical-modeling-formation-of-7hydroxymethotrexatefrommethotrexate-in-patients-undergoing-treatment-for-psoriasiswithmethot-2157-7609-1000205.php?aid=73037
Where they will and example describing mathematical modeling formation of 7-hydroxymethotrexate from methotrexate in patients undergoing treatment for psoriasis with methotrexate, using an advanced mathematical modeling method based on the theory of dynamic systems.