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Pharmaco-Resistant Epilepsy Secondary to Occipital Ulegyria | OMICS International
ISSN: 2329-6895
Journal of Neurological Disorders
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Pharmaco-Resistant Epilepsy Secondary to Occipital Ulegyria

Sira Carrasco García de León*, José Javier Bravo-Gómez, María Gudín Rodríguez-Magariños and Amalia Hernández-González

Department of Neurology, University General Hospital of Ciudad Real, Spain

*Corresponding Author:
Sira Carrasco García de León
Department of Neurology
University General Hospital of Ciudad Real, Spain
Tel: +27219593229/2190
Fax: +278615107002
E-mail: [email protected]

Received date: July 07, 2016; Accepted date: July 08, 2016; Published date: July 09, 2016

Citation: León SCG, Bravo-Gómez JJ, Rodríguez-Magariños MG, Hernández-González A (2016) Pharmaco-Resistant Epilepsy Secondary to Occipital Ulegyria . J Neurol Disord 4: i004. doi:10.4172/2329-6895.1000i004

Copyright: © 2016 García de León SC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Our patient is a 47-year-old woman. She suffered from prolonged labour at birth which was further complicated by meconial aspiration. Neurological exploration was normal. At age 11, she started experiencing partial complex seizures, consisting on sudden lapses of consciousness with motor automatisms (chewing, sucking, bimanual movements). Afterwards she would stare blankly and remain arreactive for a minute, later showing poscritic confusion. Frequency of these episodes was high, even happening several times a day. 3-Tesla Magnetic Resonance Imaging (MRI) of the brain showed an area of focal atrophy in the left occipital pole with ulegyric pattern criteria (Figure 1). Video-EEG monitoring found no anomalies. Currently she is under treatment with levetiracetam (3 g/day), lamotrigine (500 mg/ day) and clonazepam (2 mg/day), with partial control of the seizures.


Figure 1: Brain MRI imaging. T2 and coronal FLAIR sequences, showing area of ulegyria involving the left occipital lobe.

Ulegyria is a cortical injury that mostly affects posterior regions [1,2]. Its pathophysiology is based on diminished vascular flow. It is an important cause of occipital epilepsy. Seizures are usually limited to the occipital region [1,2]. Unlike what has been reported in the literature, our patient did not show localising symptoms, but her seizures' semiology suggested a temporal origin (infrasylvian propagation).


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