alexa Prologue to the Special Issue: Age-Related Macular Degeneration | Open Access Journals
ISSN: 2155-9570
Journal of Clinical & Experimental Ophthalmology
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Prologue to the Special Issue: Age-Related Macular Degeneration

Delu Song*
Scheie Eye Institute, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA USA
Corresponding Author : Delu Song MD, PhD
Scheie Eye Institute
University of Pennsylvania
Perelman School of Medicine
Philadelphia, PA USA
E-mail: [email protected]
Received: December 02, 2015 Accepted: December 07, 2015 Published: December 09, 2015
Citation: Song D (2015) Prologue to the Special Issue: Age-Related Macular Degeneration. J Clin Exp Ophthalmol 6:e116. doi: 10.4172/2155-9570.1000e116
Copyright: © 2015 Song D. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at Pubmed, Scholar Google

Visit for more related articles at Journal of Clinical & Experimental Ophthalmology

Editorial

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss among people age 50 and older. Based on the presence or absence of blood vessels, it is classified into two types, wet and dry. In the past decades, significant progress has been made in understanding the molecular mechanisms underlying wet AMD, and several robust therapeutic drugs were developed to block the development of new blood vessels and leakage from the abnormal vessels with favorable clinical effect.

In contrast, there are no approved treatments for dry AMD and the mechanisms are not completely known. However, it has been approved that genetics, complement dysregulation, oxidative stress, mitochondria DNA damage were involved in the mechanisms. Variety of scientific studies, including gene replacement therapy, retinal cell transplantation, pharmaceutical intervention and vitamin dietary supplementation, hold promise in developing treatment to prevent or slow the progression of the disease. In the clinical aspect, multiple clinical studies and trials have been done to further our knowledge of AMD, and ongoing studies are raising hopes for improved treatments.

This special issue is dedicated to present latest advances in studies of retinal degenerated diseases, including clinical studies, case reports, epidemiological analysis, as well as basic science studies related to the retina and AMD. In this special issue we aim to highlight the extent to which molecular biology in the retina and its relationship with AMD. Specifically, we seek manuscripts that how biological changes in different cell types, e.g., Muller cells, photoreceptors and retinal pigmented epitheliums, contributed to the AMD development. In addition, new therapeutic targets and approaches in the treatment of dry AMD are also of interest. We welcome all formats of manuscript like review articles, short communications/reports and original research papers. We wish to acknowledge and sincerely thank many authors, reviewers and journal personnel for their hard work and dedicated efforts.
 
Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Recommended Conferences

Article Usage

  • Total views: 7832
  • [From(publication date):
    December-2015 - Jun 27, 2017]
  • Breakdown by view type
  • HTML page views : 7787
  • PDF downloads :45
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords