Reach Us +44-1235-425476
Scleral and Body Hyperpigmentation in Disseminated Tuberculosis with Adrenal Insufficiency (Addisons Disease) | OMICS International
ISSN: 2329-9126
Journal of General Practice
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Scleral and Body Hyperpigmentation in Disseminated Tuberculosis with Adrenal Insufficiency (Addisons Disease)

Muzamil Latief1, Waseem Raja2*, Manzoor Parry1 and Ravi Rao1
1Department of Internal Medicine, University Ambala, Maharishi Markandeshwar, Haryana
2Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Jammu & Kashmir, India
*Corresponding Author : Waseem Raja
Department of Internal Medicine
Sher-i-Kashmir Institute of Medical Sciences
Jammu & Kashmir, India
Tel: +918222800676
E-mail: [email protected]
Received: February 24, 2016 Accepted: March 02, 2016 Published: March 11, 2016
Citation: Latief M (2016) Scleral and Body Hyperpigmentation in Disseminated Tuberculosis with Adrenal Insufficiency (Addison’s Disease). J Gen Practice 4:i002. doi: 10.4172/2155-6105.1000i002
Copyright: © 2016 Latief M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of General Practice

Clinical Image
A 25 years old gentleman was diagnosed with Pulmonary Tuberculosis 1 year back and started on Anti Tuberculosis Treatment (ATT) 4 Drugs (Isoniazid, Rifampin, Pyrazinamide and Ethambutol). He took these medications for a period of 6 weeks and stopped the medication on his own. He never returned to any healthcare facility until he presented to us with complaints of weight loss for last 6 months, progressive skin hyperpigmentation and nausea for 4 weeks before presenting to us. On presentation, there was diffuse hyperpigmentation of whole body including buccal mucosa, tongue and sclera (Figures 1-3). He was in hypotension with tachycardia. Investigations revealed hyponatremia with random serum cortisol 8 nmol/L and Post ACTH stimulation, cortisol levels at 30 minutes and 60 minutes were <11 nmol/L. Serum ACTH levels were high. Abdominal Imaging revealed bilateral Adrenal Enlargement. Patient was started on IV fluids and IV steroids (Hydrocortisone 50 mg 6 hourly) and Anti-Tuberculosis Treatment (Isoniazid, Rifampin, Pyrazinamide, Ethambutol and Streptomycin). His hemodynamic parameters improved during hospital stay, nausea and anorexia settled. Subsequently patient was discharged on oral steroids Hydrocortisone 20 mg twice a day and Fludricortisone 100 mcg/day and made to continue ATT. Patient is doing well on follow up.

Figures at a glance

Figure Figure Figure
Figure 1 Figure 2 Figure 3
Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

  • International Conference on Internal Medicine
    October 24-25, 2018 Osaka, Japan
  • Annual Congress on Medicine
    November 05-06, 2018 London, Thailand
  • 7th International Conference on Clinical and Medical Case Reports
    November 08-09, 2018 Sydney, USA
  • International Conference on Alternative Medicine & Annual Physicians Meet
    November 12-13, 2018 London, Japan

Article Usage

  • Total views: 9050
  • [From(publication date):
    April-2016 - Oct 20, 2018]
  • Breakdown by view type
  • HTML page views : 8932
  • PDF downloads : 118

Review summary

  1. Tianna Wells
    Posted on Oct 17 2016 at 5:04 pm
    The publication of clinical images is a very novel and rewarding concept. It not only enhances the clinical importance of the article but also helps in diagnosis of similar diseases in future. The present article educates us regarding the possible consequences of discontinuation of ATT therapy in tuberculosis patients as well as diagnosis and treatment of Addison’s disease.

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version