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Spine Fracture in Ankylosing Spondylitis. About a Case | OMICS International
ISSN: 2161-1149
Rheumatology: Current Research

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Spine Fracture in Ankylosing Spondylitis. About a Case

Maria Jose Moreno Martinez1*, Manuel Jose Moreno Ramos2 and Luis F. Linares Ferrando2

1Rheumatology, Hospital Rafael Mendez, Lorca, Murcia, Spain

2Rheumatology, H. C. U. Virgen Arrixaca, Murcia, Spain

*Corresponding Author:
Maria Jose Moreno Martinez
Rheumatology, Hospital Rafael Mendez
Lorca, Murcia, Spain
Tel: 0034-647810640; 0034-968369534
E-mail: [email protected]

Received date: March 07, 2016; Accepted date: April 25, 2016; Published date: April 28, 2016

Citation: Martinez MJM, Ramos MJM, Ferrando LFL (2016) Spine Fracture in Ankylosing Spondylitis. About a Case. Rheumatology (Sunnyvale) 6:194. doi:10.4172/2161-1149.1000194

Copyright: © 2016 Martinez MJM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease. The natural evolution of AS leads to a spinal fusion by the formation of bony ridges and diffuse spinal stiffness [1]. The inflammation and this diffuse stiffness exposes the spine to risks of fractures as a result of minor trauma [1].


We report the case of a 44 year old man diagnosed with AS, with peripheral involvement, ten years ago. The patient suffered an accidental fall and he was attended the emergency room for neck pain without motor or sensory disorders. In the cervical spine radiographs no obvious changes are evident, so it was performed computerized tomography (CT) (Figure 1). He was diagnosed with non-displaced odontoid fracture. Prior to this event, the patient had a normal densitometry and bone metabolism analytical. During follow-up he had remained stable, without signs of neurologic involvement.


Figure 1: CERVICAL CT (axial (upper) and sagittal (lower)): fracture through body of C2 (odontoid) without displacement.


AS increases the risk of vertebral fractures. The risk of fracture following trauma increases with the time since the diagnosis and occur more frequently in cases of AS with peripheral involvement [1]. Fractures are favoured by the loss of elasticity [2]. These fractures are cervical in 75% of the cases and they predominate at the lower levels (from C5 to C7) [1-3]. We report the case of a rare cervical fracture; C2.

Some studies have analysed vitamin D levels and bone mass in patients with AS, looking down on it, especially in early stages [4]. There has been a decrease in bone mass measured by DEXA (dual energy X) at the hip, in those patients with AS compared to controls. Thus finding no differences at the level of the lumbar spine [2]. This may be due to the existence of syndesmophytes, bridges sindesmofíticos and calcification of ligaments. Our patient had no laboratory abnormalities and DEXA was normal.


The risk of fractures is increased in patients with AS for different reasons. The usual imaging techniques may not be sufficient in this pathology, requiring others such as CT.


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