alexa Studies and application of Nanomotor for Single Pore Sensing, Single Fluorescence Imaging, and RNA Nanotechnology | OMICS International
ISSN: 2161-1009
Biochemistry & Analytical Biochemistry
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Studies and application of Nanomotor for Single Pore Sensing, Single Fluorescence Imaging, and RNA Nanotechnology

Peixuan Guo, Ph.D*

William Farish Endowed Chair in Bionanotechnology, Director of Nanobiotechnology Center, University of Kentucky, USA

*Corresponding Author:
PeixuanGuo
Director of NanobiotechnologyCenter
University of Kentucky, USA
Tel: Phone: (859) 218-0128
Email: [email protected]

Received Date: June 29, 2015; Accepted Date: June 30, 2015; Published Date: July 02, 2015

Citation: PeixuanGuo(2015) Studies and application of Nanomotor for Single Pore Sensing, Single Fluorescence Imaging, and RNA Nanotechnology. Biochem Anal Biochem 4: i105. doi:10.4172/2161-1009.1000i105

Copyright: © 2015 PeixuanGuo. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Biochemistry & Analytical Biochemistry

DsDNA translocation motors are essential for DNA replication, repair, homologious recombination, chromosome segregation, bacterial devision, viral DNA packagin, and DNA/RNA trasport within cells.

equation

equation

Guo P. et al. Science, 1987

Guo P. et al. PNAS, 1986

Guo, P. et al. Mol Cell, 1998

Four major discoveries

(see movies from NIH director Dr. Collins’ office web site) https://www.youtube.com/watch?v=rRGYHFulzkQ

•1. Discovery of a third category of biological motor by revolution mechanism without rotation (https://www.youtube.com/watch?v=LpUGuEQos6Y).

•2. Insertion of the motor channel into membrane for ultrasensitive earlier cancer diagnosis; single molecule sensing, and potential single pore DNA sequencing (https://www.youtube.com/watch?v=rRGYHFulzkQ).

•3. Leading to the emergence of a new field of RNA nanotechnology with potential application in cancer treatment extremely low organ accumulation and side effect (https://www.grc.org/programs.aspx?id=16896)

•4. Discovery of a new approach to develop ultra-high potent inhibitory drug for anti-drug resistance in cancer, bacterial or viral infection.

•(https://www.sciencedaily.com/releases/2015/07/150708100738.htm)

Phi29 bacteriophage dsDNA packaging motor

The left-handed channel and the right-handed DNA with anti-parallel
conformation supports the revolution, but not the rotation mechanism.

equation

UK's Guo Discovers New Class of Revolving Biomotor

• Previously, two types of biomotors had been discovered:

a. Linear Motor b. Rotation Motor

• Recently, we discovered a third type --- revolution motor:

References

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Article Usage

  • Total views: 7952
  • [From(publication date):
    specialissue-2015 - Dec 11, 2017]
  • Breakdown by view type
  • HTML page views : 7888
  • PDF downloads : 64
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version