alexa Wade’s Histoid Leprosy Dermatofibroma Like | Open Access Journals
ISSN: 2157-7099
Journal of Cytology & Histology
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Wade’s Histoid Leprosy Dermatofibroma Like

Avalos Peralta Patricia1 and Di Martino Ortiz Beatriz2*

1Hospital Británico, Asunción, Paraguay

2Department of Dermatology, Faculty of Medical Sciences, National University, Clinical Hospital, Asunción, Paraguay

*Corresponding Author:
Di Martino Ortiz Beatriz
Associate Professor of Dermatology, Dermatopathologist
Dermatology Department, Clinical Hospital
Faculty of Medical Sciences
National University, Asunción, Paraguay
Tel: 595-21-446 991
E-mail: [email protected]

Received date: June 01, 2017; Accepted date: June 20, 2017; Published date: June 30, 2017

Citation: Patricia AP, Beatriz DMO (2017) Wade’s Histoid Leprosy Dermatofibroma Like. J Cytol Histol 8: 460. doi:10.4172/2157-7099.1000460

Copyright: © 2017 Patricia AP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Cytology & Histology


A healthy 52-year-old phototype II woman, farmer, with a 6 months history of asymptomatic slow growing papules and nodules, first at the upper lip, then extended to the forearms, shoulders, legs and back.

Image Article

A healthy 52-year-old phototype II woman, farmer, with a 6 months history of asymptomatic slow growing papules and nodules, first at the upper lip, then extended to the forearms, shoulders, legs and back. She referred burning sensation in both arms when exposed to sunlight (Figure 1).


Figure 1: Leprosy Dermatofibroma.

On physical examination, a well-demarcated shiny papulo-nodular lesión of 1 cm at the upper lip was detected. Also on both forearms and shoulders there was erythema and small papules with a diameter ranged from 0,3 to 0,5 cm (Panel A). On the left wrist there was a painless, firm and pale pink dome shaped nodular lesion of 1 cm of diameter (Panel B). She has lesions on both legs of the same characteristics (Panel C). We performed excision of two papules. Histopathology revealed circumscribed nodular lesions consisting predominantly of spindle-shaped cells with some polygonal forms. The cells were arranged in an intertwining pattern, resembling a fibrohistiocytic tumor (Panel D). Small collections of foamy macrophages were also present (Panel E) and Fite Faraco stain shows heavily parasitized macrophages (Panel F). Routine laboratory studies were normal. Lepromatous leprosy (LL) histioid variant of Wade is a form of multibacillary leprosy presenting with specific clinical, histopathological and bacteriological features, which may arise de novo or after inadequate and irregular treatment with dapsone monotherapy or combination polichemotherapy. This variety is rare and raises many differential diagnoses such as multiples dermatofibromas, nodular basal cell carcinoma, fibromas, neurofibromas, eruptive xantomas and lymphomas. We should point out: 1. The importance of early diagnosis and treatment, as the high load of BI in the smears, the patient is a significant reservoir of the disease, and 2. The importance of long-term monitoring during and after treatment of patients with histioid LL. The patient is receiving multidrug therapy (WHO) for multibacillary leprosy.

Conflict of Interests

The authors declare no conflict of interests.

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Article Usage

  • Total views: 281
  • [From(publication date):
    June-2017 - Oct 18, 2017]
  • Breakdown by view type
  • HTML page views : 244
  • PDF downloads :37

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version