Reach Us +1-504-608-2390
Opinion: Challenges and Safeguards - Filling the Gaps in Toxicological Research of Heavy Metals | OMICS International
ISSN: 2161-0495
Journal of Clinical Toxicology

Like us on:

Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Opinion: Challenges and Safeguards - Filling the Gaps in Toxicological Research of Heavy Metals

Noreen Khan-Mayberry*

Aerospace Toxicologist, Science and Aeronautics Research Directorate, NASA, USA

*Corresponding Author:
Noreen Khan-Mayberry
Aerospace Toxicologist
Science and Aeronautics Research Directorate, NASA, USA
E-mail: [email protected]

Received date: September 02, 2013; Accepted date: September 04, 2013; Published date: September 07, 2013

Citation: Khan-Mayberry N (2013) Opinion: Challenges and Safeguards - Filling the Gaps in Toxicological Research of Heavy Metals. J Clin Toxicol 3:e121. doi: 10.4172/2161-0495.1000e121

Copyright: © 2013 Khan-Mayberry N. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Clinical Toxicology


Anthropogenic sources of heavy metals from a wide array of domestic and international sources in industry, technology, medicine, agricultural, technological, have long raised concerns of their effects on human health and environmental health. Heavy metals are widely accepted as highly toxic, hence their high ranking as chemical of public concern. Yet much of what we know in the scientific community regarding are sole source or exposures to one or two combined heavy metals. Researchers are working diligently trying to fill in the gaps for the determination of toxic mode of action, chronic effects of trace exposures to heavy metals, methods to diagnose disease caused by environmental factors. The complexity lies in the fact that the laboratory bench cannot effectively simulate real world exposures. While technology and research methods continue to evolve, many of these new assays still struggle to characterize the toxicity of more than one heavy metal. We must continue to develop and test new assays and develop methodologies that pull from multiple assays in order to create the most complete and accurate toxicological characterizations. As scientists, we are obligated to continue to conduct meaningful research that will better help toxicologists more accurately illustrate the acute and chronic health effects from chemical mixtures. Heavy metals are already classified as known or probably carcinogens and are known systemic toxicants that cause damage to multiple organs. Determining the mechanisms of systemic and targeted toxicity are critical in order to make risk assessments and set environmental health standards that are as accurate as possible. Heavy metal toxicity depends on multiple physicochemical and biological factors, including chemistry, dose, and concentration, duration of exposure as well as genetics, age, gender, nutritional status, health status, and route of exposure. It is incumbent on research investigators, that we not only work to make accurate assessments, but strive to ensure that bias does not enter into our findings by rigorous documentation, clear statements of gaps in findings and critical future work, peer review and collaboration. This will not only safeguard the integrity of our findings but will bolster our data and conclusions against skeptics. As our exposures to heavy metals remains ever present in our environment, so too will the public interest in the long-term effects on our health.


The views expressed in the article do not necessarily represent the views of NASA, any Federal Agency or the United States.

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Article Usage

  • Total views: 11731
  • [From(publication date):
    December-2013 - Jan 17, 2019]
  • Breakdown by view type
  • HTML page views : 7959
  • PDF downloads : 3772

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version