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Peng et al. assessed the cost-effectiveness of staging diagnostic laparoscopy (SDL) in borderline resectable pancreatic cancer. Data was retrospectively collected from a single institution. A total of 116 patients were identified, of which 102 (88%) were candidates for neoadjuvant therapy. Seventy-six (75%) of these patients underwent SDL, while 26 (25%) were planned for neoadjuvant chemotherapy without SDL. Tumors in the two groups had similar characteristics including size and arterial or venous involvement. Nineteen of the 75 (25%) patients who underwent SDL were found to have evidence of metastatic disease due to metastatic implants or cytology findings. While no significant difference was found in the overall costs to patients who undergo SDL prior to treatment. However, 25% of patients undergoing SDL had a change in their treatment pathway due to positive SDL findings, suggesting SDL may merit further study.
Citation: Peng JS et al. Diagnostic Laparoscopy to Detect Occult Metastatic Disease Prior to Neoadjuvant Chemoradiation in Borderline Resectable Pancreatic Ductal Adenocarcinoma - A Cost Analysis. Paper presented at the 48th Annual Meeting of the Pancreas Club; May 2014; Chicago, Illinois, USA.
Last date updated on July, 2014