2-(2-(2-Hydroxybenzyliden) Hydrazinyl)-2-Oxo-N-(Pyridine-2-Yl) Acetamide Complexes: Synthesis, Characterization and Biological StudiesYasmeen Gaber Abou El-Reash, Rania Zaky* and Mahmoud Abbas Yaseen
Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt
- *Corresponding Author:
- Rania Zaky
Department of Chemistry
Faculty of Science, Mansoura University
E-mail: [email protected]
Received date: November 01, 2016; Accepted date: December 05, 2016; Published date: December 08, 2016
Citation: El-Reash YGA, Zaky R, Yaseen MA (2016) 2-(2-(2-Hydroxybenzyliden) Hydrazinyl)-2-Oxo-N-(Pyridine-2-Yl) Acetamide Complexes: Synthesis, Characterization and Biological Studies. Chem Sci J 7:145. doi: 10.4172/2150-3494.1000145
Copyright: © 2016 El-Reash YGA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
2-(2-(2-hydroxybenzyliden) hydrazinyl)-2-oxo-N-(pyridine-2-yl) acetamide complexes of Ni(II) and Co(II) prepared. The proposed structures proved based on elemental, DFT, and spectral analysis. The DNA binding affinity and MIC activity against Gram-positive, Gram-negative bacteria, pathogenic C. albicans and A. flavus fungal strain tested.