A 6-weeks Treatment Program Improves HRV in Eating Disorder Patients
- *Corresponding Author:
- Herbert Jelinek
School of Community Health
Thurgoona Drive, Albury
E-mail: [email protected]
Received date: May 13, 2016; Accepted date: May 18, 2016; Published date: May 25, 2016
Citation: Jelinek HF, Tarvainen MP, Cornforth DJ, Spence I, Russell J (2016) A 6-weeks Treatment Program Improves HRV in Eating Disorder Patients. J Med Diagn Meth 5:211. doi:10.4172/2168-9784.1000211
Copyright: © 2016 Jelinek HF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Eating disorders such as anorexia nervosa present with a significant cardiovascular associated risk of sudden cardiac death. Bradycardia is a serious complication of eating disorders.
Methods: Eating Disorder (ED) patients were admitted to a 6-week treatment program and assessed for of heart rate variability (HRV) at entrance to the program and at discharge from hospital. Linear heart rate variability measures were determined using Kubios software from Lead 3 ECG recordings following a 5-minute rest period. Nonparametric statistics were applied and significance set at p < 0.05.
Results: No significant differences in HRV parameters were noted for the control group following the 6-week treatment program. For the ED group, mean RR interval length decreased significantly following treatment compared (median ± IQR; -64 ± 76; p = 0.002). Sympathovagal function was abnormal in the ED group on admission but improved following treatment, showing a decrease in RMSSD (median ± IQR; -9 ± 18; p = 0.048) and SD1 (median ± IQR; -6 ± 13; p = 0.048). Sample entropy, a, measure of heart rate complexity did not change significantly.
Conclusion: At admission to hospital the ED group was more parasympathetic during rest compared to controls, but they became more sympathetic after the intervention and approached the HRV measures of the controls.