A Brief Overview of Hyperthermia in Cancer TreatmentGianfranco Baronzio1*, Gurdev Parmar2, Marco Ballerini1, Andras Szasz3, Miriam Baronzio1 and Valter Cassutti1
- *Corresponding Author:
- Baronzio Gianfranco
Scientific Director of Demetra ML Cell Factory and Hyperthermia /Immunity Center
Via Cassian Bon 1/A, 05100 Terni, Italy
Tel/Fax: +39-331 881712
E-mail: [email protected]
Received date April 22, 2014; Accepted date May 15, 2014; Published date June 01, 2014
Citation: Baronzio G, Parmar G, Ballerini M, Szasz A, Baronzio M, et al. (2014) A Brief Overview of Hyperthermia in Cancer Treatment. J Integr Oncol 3:115. doi:10.4172/2329-6771.1000115
Copyright: © 2014 Baronzio G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Despite the large economic and intellectual efforts, cancer is still not easily treatable disease by conventional therapies. This led ultimately to reconsider hyperthermia, like one of interesting treatment methods connected to immunity and tumor metabolism. Hyperthermia has also the ability to play an additional role when used together with the conventional methods of treatment: surgery, radiotherapy, chemotherapy and immunotherapy. Recent trials in Holland and Germany have demonstrated that hyperthermia can prolong life and decrease disease re-appraisal when used in combination with radiotherapy and chemotherapy. Some tumors seem more responsive than others. In this brief summary we will attempt to give a vision of hyperthermia from a physical stand point, but more importantly we will give clinical and biological aspects. The results obtained in these trials on certain types of cancers such as cervix cancer, recurrent breast cancer and head neck cancer, melanoma, sarcomas, liver, glioblastoma and pancreatic cancer support the use of this technique, although some clinical and technical problems persist and have not been completely resolved.