alexa A Brief Overview on Recent Advances in the Development of Anti-Tubercular Compounds Containing Different Heterocyclic Ring Systems | OMICS International | Abstract
ISSN: 2471-9315

Applied Microbiology: Open Access
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Review Article

A Brief Overview on Recent Advances in the Development of Anti-Tubercular Compounds Containing Different Heterocyclic Ring Systems

Mohammad Asif*

Department of Pharmacy, GRD (PG) Institute of Management and Technology, Dehradun, Uttarakhand, India

*Corresponding Author:
Mohammed Asif
Department of Pharmacy
GRD (PG) Institute of Management and Technology
Dehradun, Uttarakhand, India
Tel: +91 92580-71905
Fax: +91 135 273-4048
E-mail: [email protected]

Received date: August 02, 2016; Accepted date: August 24, 2016; Published date: August 29, 2016

Citation: Asif M (2016) A Brief Overview on Recent Advances in the Development of Anti-Tubercular Compounds Containing Different Heterocyclic Ring Systems. Appli Micro Open Access 2: 1000122. doi:10.4172/2471-9315.1000122

Copyright: © 2016 Asif M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Tuberculosis (TB), a leading cause of mortality and morbidity with more than one-third of the world population infected with latent TB and the worldwide dissemination of multidrug (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis poses a serious threat to human health. Hence, new drugs are urgently needed to shorten and improve the treatment course in drug resistant TB, and to minimize the occurrence of new infections and death to zero level. Various new drugs progress to be developed for the treatment of MDR-TB. Several new molecules in clinical development encourage the scientific community to find new drug targets and new drug leads. In this perspective we present herein an overview of the new anti-TB agents with different molecular structures. Here we have tried to provide some efforts that are being made in the development of new drug molecules as lead anti- TB agents.

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