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ISSN: 2167-0501

Biochemistry & Pharmacology: Open Access
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Editorial

A Brief Overview on the Intracellular Regulation of Aquaporins by Pharmacological Agents

Marcelo Ozu*
Department of Physiology and Biophysics, School of Medicine, University of Buenos Aires, Argentina
Corresponding Author : Marcelo Ozu
Department of Physiology and Biophysics
School of Medicine, University of Buenos Aires
Paraguay 2155, 7th Floor
C1121ABG City of Buenos Aires
Buenos Aires, Argentina
Tel: +054-11-4964-0503
Fax: +054-11-4964-0503 ext. 23
E-mail: [email protected], [email protected]
Received August 24, 2012; Accepted August 25, 2012; Published August 27, 2012
Citation: Ozu M (2012) A Brief Overview on the Intracellular Regulation of Aquaporins by Pharmacological Agents. Biochem Pharmacol 1:e131. doi:10.4172/2167-0501.1000e131
Copyright: © 2012 Ozu M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

This Editorial makes a brief description of the principal pharmacological agents that have demonstrated effect on the transport properties of animal aquaporins. The recent discoveries of intracellular inhibitors, such as bumetanide and furosemide are included. Finally, studies for comprehension of gating mechanisms in aquaporins are mentioned as perspectives for future research.

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