A Case of Inflammatory Reduction with Ozone Treatment of Disc Herniation and Histological ChangesDario Apuzzo1, Paolo Ferrazza2*, Marchilia Piscitelli2 and Ergena Melengu2
- *Corresponding Author:
- Paolo Ferrazza
Centro Clinical Research LNage S.r.l, Link Neuroscience and
Health Care, Via Luigi Rizzo, 62, 00136 Rome, Italy
E-mail: [email protected]
Received Date: March 08, 2016; Accepted Date: April 21, 2016; Published Date: April 29, 2016
Citation: Apuzzo D, Ferrazza P, Piscitelli M, Melengu E (2016) A Case of Inflammatory Reduction with Ozone Treatment of Disc Herniation and Histological Changes. Anat Physiol 6:217. doi: 10.4172/2161-0940.1000217
Copyright: © 2016 Apuzzo D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objectives: Ozone therapy can stop pain caused by the intervertebral disc degeneration, associated with an extrusion of nucleus pulpous that cause inflammatory changes.
Materials and methods: Bilateral intramuscular O2O3 infiltrations, injected on the disk lesion site with a paravertebral approach. An Oxygen-Ozone mixture at a rate of 20 μg/ml was obtained by means of an Ozone generator.
Results: The loss of matrix components of nucleus pulpous herniation causes pain due to stimulation of inflammation and not caused by mechanical nerve pressure.
Conclusion: The action of oxygen-ozone is the regeneration of the annulus fibrosus of disc herniation and reduction of inflammatory chain generation. It is also confirmed by the persistence of the mechanical pressure on the nerve but the inflammatory and pain symptoms have disappeared.