alexa A Case of Temporal Artery Dissection in a Patient with Giant Cell Arteritis | OMICS International
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

A Case of Temporal Artery Dissection in a Patient with Giant Cell Arteritis

Shubha Kollampare*, Wendy Mackerricher, Dominick Sudano, Rafael Grau and Jeffrey Lisse
University of Arizona, Tucson, USA
*Corresponding Author : Shubha Kollampare
University of Arizona, Tucson, USA
Tel: +1 520-621-2211
E-mail: [email protected]
Received: January 11, 2016; Accepted: February 22, 2016; Published: February 26, 2016
Citation: Kollampare S, Mackerricher W, Sudano D, Grau R, Lisse J (2016) A Case of Temporal Artery Dissection in a Patient with Giant Cell Arteritis. J Clin Case Rep 6:723. doi:10.4172/2165-7920.1000723
Copyright: © 2016 Kollampare S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Giant cell arteritis (GCA) is a chronic vasculitis involving medium and large sized arteries. A 73-year-old male presented with right eye visual loss and jaw claudication associated with photosensitivity, supraorbital and retrobulbar pain. Evaluation demonstrated bitemporal tenderness, elevated ESR, CRP, leukocytosis and positive PANCA. Stranding and abnormal enhancement of right retrobulbar fat along the optic nerve sheath complexes was noted on MRI. Emergent biopsy of right temporal artery showed giant cell infiltration, disruption of internal elastic lamina with medial dissection. Despite steroid therapy, blurry vision in the left eye progressed to blindness. Tocilizumab infusion was initiated without much improvement. Interleukin 6 levels correlate with disease activity and severity in GCA. Glucocorticoids reduce inflammation by decreasing IL-6; however in refractory cases, the use of interleukin 6 antagonists may aid in rapid induction of remission. Blindness is a serious and irreversible complication of GCA, which makes early detection and treatment paramount.

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