alexa A Case Report of Atypical Teratoid/Rhabdoid Tumor with Diffuse Leptomeningeal Carcinomatosis and Review of Current Literature
ISSN: 2472-100X

Journal of Pediatric Neurology and Medicine
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Case Report

A Case Report of Atypical Teratoid/Rhabdoid Tumor with Diffuse Leptomeningeal Carcinomatosis and Review of Current Literature

Vanessa Baute*

Wake Forest Baptist Medical Center, Winston Salem, North Carolina, USA

*Corresponding Author:
V anessa Baute
Assistant Professor of Neurology
W ake Forest Baptist Medical Center
Winston Salem, North Carolina, USA
T el: 336-716-4101
E-mail: [email protected]

Received date: May 23, 2017; Accepted date: June 14, 2017; Published date: June 21, 2017

Citation: Baute V (2017) A Case Report of Atypical Teratoid/Rhabdoid Tumor with Diffused Leptomeningeal Carcinomatosis and Review of Current Literature. J Pediatr Neurol Med 2:122. doi:10.4172/2472-100X.1000122

Copyright: © 2017 Baute V. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



We present a rare case of craniospinal atypical teratoid/rhabdoid tumor (ATRT) with leptomeningeal carcinomatosis in young adult. A previously healthy 25 year old man presented to the hospital after a one week history of intermittent confusion, intractable headache and a single new onset seizure. Two lumbar punctures were completed and both revealed elevated RBC, elevated protein and predominantly lymphocytic pleocytosis. Both lumbar punctures were unrevealing with normal cytology and flow cytometry. Contrasted magnetic resonance imaging (MRI) of the brain revealed extensive intracranial leptomeningeal and cranial nerve enhancement. Contrasted MRI of the spinal cord revealed extensive leptomeningeal and dural enhancement with multifocal areas of nodular mass-like enhancement along the entire spinal cord. Spinal biopsies were performed and a pathological diagnosis of ATRT was made. Aggressive radiotherapy and chemotherapy treatment were started. Unfortunately, the patient expired within 12 months of the initial diagnosis.


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