A Case Report of Immunoglobulin A-dominant Acute Postinfectious Glomerulonephritis in a Patient with a Horseshoe Kidney
- *Corresponding Author:
- S. Alexander Woods
University of Tennessee Health Science Center
956 Court Street, Suite H314, Memphis, TN 38163, USA
E-mail: [email protected]
Received date: October 19, 2015; Accepted date: November 23, 2015; Published date: November 30, 2015
Citation: Woods SA, Trivedi DD, Naseer A, Huch KM, Gyamlani G (2015) A Case Report of Immunoglobulin A-dominant Acute Postinfectious Glomerulonephritis in a Patient with a Horseshoe Kidney. J Kidney 1:104. doi:10.4172/2472-1220.1000104
Copyright: © 2015 Woods SA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Immunoglobulin A-dominant acute postinfectious glomerulonephritis (IgA-dominant APIGN) is an increasingly recognized morphologic variant of APIGN. In contrast to classic APIGN, in which there is glomerular deposition of IgG and/or C3, IgA is the sole or dominant immunoglobulin deposited in IgA-dominant APIGN. Patients present with declining glomerular filtration rate (GFR), proteinuria, and microscopic hematuria. Horseshoe kidney (HSK) is a relatively common renal anomaly. To this point, the co-occurrence of HSK and IgA-dominant APIGN has not been reported in the literature. Here, we report a case of IgA-dominant APIGN in a patient with HSK resulting in the need for temporary hemodialysis.