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  • Case Report   
  • Pharamcoeconomics,
  • DOI: 10.4172/2472-1042.1000108

A Case Report of Prototheca Meningitis in China

Li YT, Zeng YF, Ning G, Gan WQ and Lin CS*
Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, , Guangzhou 510630, China
*Corresponding Author : Lin CS, Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China, Tel: 020-85253008, Fax: 020-85252559, Email: [email protected]

Received Date: Mar 21, 2016 / Accepted Date: May 02, 2016 / Published Date: May 09, 2016

Abstract

Human prototheca meningitis was rarely reported in the world; here we present another case report. A 23 year old young man was admitted to department of infectious disease of the third affiliated hospital of Sun Yat-sen university, complaining of fever, headache and vomiting. Before admission, he had been diagnosed as tuberculous meningitis. After taking chemical therapy with antituberculous drugs combined with adrenocortical hormones for two months, his condition deteriorated. Cerebrospinal fluid (CSF) was collected through lumbar punture for the patient, and prototheca species, which was sensitive to amphotericin B and nystatin, was discovered in CSF after culture. During hospitalization, the patient’s condition once ameliorated when the total amount of amphotericin B reached to 2400 mg three months later. However, the secondary bacterial infection in central nervous system, abdomen, and lungs might contribute to the death of the patient when amphotericin B reached to 6000 mg after 11 months. Prototheca species, though rarely been described, may also have a significant pathogenic potential in human.

Keywords: Prototheca; Meningitis; Amphotericin B; Nystatin

Citation: Li YT, Zeng YF, Ning G, Gan WQ, Lin CS (2016) A Case Report of Prototheca Meningitis in China. Pharmacoeconomics 1:108. Doi: 10.4172/2472-1042.1000108

Copyright: © 2016 Li YT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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