alexa A Case Study of Partial Seizure with Secondary Generalization Induced by Clozapine in Patient with Treatment Resistant Schizophrenia | OMICS International | Abstract
ISSN: 2168-975X

Brain Disorders & Therapy
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Case Report

A Case Study of Partial Seizure with Secondary Generalization Induced by Clozapine in Patient with Treatment Resistant Schizophrenia

Khalid W Al Quliti*
Department of Medicine, Assistant professor and consultant of Neurology, College of Medicine, Taibah University, Consultant Neurology, National guard hospital-Madinah, Madinah Munawarah, Saudi Arabia
Corresponding Author : Dr. Khalid W Al Quliti. MD
Chairman, Department of Medicine
Assistant professor and consultant of Neurology
College of Medicine, Taibah University
Consultant Neurology, National guard hospital-Madinah
Madinah Munawarah, Saudi Arabia
Tel: +96658242577
E-mail: [email protected]
Received September 08, 2014; Accepted September 23, 2014; Published September 30, 2014
Citation: Quliti KWA (2014) A Case Study of Partial Seizure with Secondary Generalization Induced by Clozapine in Patient with Treatment Resistant Schizophrenia. Brain Disord Ther 3:145. doi:10.4172/2168-975X.1000145
Copyright: © 2014 Quliti KWA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: A patient with schizophrenia, who was resistant to treatment by several typical and atypical antipsychotic medications, was prescribed clozapine. After receiving clozapine at a high dose, he experienced two seizure episodes. Objectives: To highlight serious side effects, such as seizure, that can emerge with administration of psychotropic agents, as well as recommend approaches to intervene in these cases. Conclusion: Clinical knowledge of potential severe side effects of antipsychotic medications (e.g Clozapine) is essential and detailed clinical evaluation may help to avoid serious harm to patients as well as treatment failure.

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