alexa A Case with 7 Min Door-To-Needle-Time and an Outline of
ISSN: 2168-975X

Brain Disorders & Therapy
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Case Report

A Case with 7 Min Door-To-Needle-Time and an Outline of Ultrarapid Stroke Management

Carsten M. Klingner1*, Stefan Brodoehl1, Christian Hohenstein2, Johannes Winning3, Lars Kummer2, Otto W. Witte1 and Albrecht Günther1
1Hans Berger Department of Neurology, University Hospital Jena, Germany
2Department of Emergency Medicine, University Hospital Jena, Germany
3Department of Anesthesiology and Intensive Care Medicine, University Hospital Jena, Germany
Corresponding Author : Carsten M. Klingner, M.D
Hans Berger Clinic for Neurology, University Hospital Jena
Friedrich Schiller University, Erlanger Allee 101 D 07747 Jena, Germany
Tel: +49 3641-9323402
E-mail: [email protected]
Received November 20, 2014; Accepted November 25, 2014; Published November 30, 2014
Citation: Klingner CM, Brodoehl S, Hohenstein C, Winning J, Kummer L et al. (2015) A Case with 7 Min Door-To-Needle-Time and an Outline of Ultrarapid Stroke Management. Brain Disord Ther 4:153. doi:10.4172/2168-975X.1000153
Copyright: © 2015 Klinger CM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Tissue plasminogen activator (t-PA) is the only approved thrombolytic therapy for the treatment of stroke patients. Its effectiveness is highly time dependent due to the sensitivity of brain tissue to ischemia. Therefore, it is crucial to minimize the time between the onset of symptoms and the initiation of an effective thrombolytic treatment. Here we describe a case that received an ultrarapid thrombolytic therapy. A 72-year-old woman was presented at our emergency department with a sudden occurrence of severe left sided hemiparesis. After exclusion of intracranial hemorrhage, the patient received intravenous thrombolysis therapy 7 min after arrival at our hospital. The patient showed a fast, nearly complete improvement of symptoms, and a minor infarction was detected in a follow up MRI. We describe this case and the general stroke management in our emergency department that led to this rapid door-to-needle time.


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