A Comparison of Levobupivacaine and Ropivacaine for Interscalene and Femoral Nerve Blocks: A Randomized, Double-Blind, Prospective Clinical Trial
- *Corresponding Author:
- Marie N. Hanna, MD
Assistant Professor, Department of Anesthesiology
Johns Hopkins University, 600 N. Wolfe Street
Carnegie 280, Baltimore, MD 21287, USA
Tel: (410) 955-5608
Fax: (410) 614-1796
E-mail: [email protected]
Received Date: February 22, 2011; Accepted Date: April 17, 2011; Published Date: May 02, 2011
Citation: Hanna M, Sloan P (2011) A Comparison of Levobupivacaine and Ropivacaine for Interscalene and Femoral Nerve Blocks: A Randomized, Double-Blind, Prospective Clinical Trial. J Anesthe Clinic Res 2:135. doi: 10.4172/2155-6148.1000135
Copyright: © 2011 Hanna M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Study Objective: To compare the quality of perioperative analgesia provided by levobupivacaine 0.5% and ropivacaine 0.5%.
Design: Randomized, double-blind, prospective clinical trial.
Setting: Operating room of a university medical center.
Patients: Thirty-five patients undergoing shoulder arthroscopy and thirty-six patients undergoing anterior cruciate ligament (ACL) reconstruction.
Interventions: Patients undergoing shoulder arthroscopy were administered interscalene blocks, and patients undergoing ACL reconstruction were administered femoral nerve blocks. Patients in each group were randomized to receive either levobupivacaine 0.5% or ropivacaine 0.5%.
Measurements: On postoperative days one and two, patients reported on the time of postoperative pain onset, the time when movement resumed in the operative limb, the time when pain medication was first required, and the amount of pain medication used. Patient satisfaction was measured 48 hours after the procedure on a 1–10 verbal numeric rating scale.
Main results: Time to onset of anesthesia, intraoperative and postoperative opioid requirements, duration of postoperative analgesia, and overall patient satisfaction were similar between patients who received levobupivacaine and those who received ropivacaine.
Conclusions: The study demonstrates that levobupivacaine and ropivacaine produce comparable postoperative analgesia when used for interscalene and femoral nerve blocks.