alexa A Comparison of Perinatal Outcomes in Multiple Pregnancies: Assisted Versus Spontaneous Conception: A Cross-Sectional Study | OMICS International | Abstract
ISSN: 2375-4508

Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology
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Research Article

A Comparison of Perinatal Outcomes in Multiple Pregnancies: Assisted Versus Spontaneous Conception: A Cross-Sectional Study

Dooley W1*, Lonsdale S2, Dilgil M1, Diamantopoulos A1, Gudi A1, Shah A1, Husain S2 and Homburg R1
1Fertility Unit, Homerton University Hospital NHS Foundation Trust, United Kingdom
2Neonatal Unit, Homerton University Hospital NHS Foundation Trust, United Kingdom
*Corresponding Author : William Dooley
Fertility Unit, Homerton University Hospital, United Kingdom
Tel: 07841677473
E-mail: [email protected]
Received February 17, 2016; Accepted March 10, 2016; Published March 17, 2016
Citation: Dooley W, Lonsdale S, Dilgil M, Diamantopoulos A, Gudi A, et al. (2016) A Comparison of Perinatal Outcomes in Multiple Pregnancies: Assisted Versus Spontaneous Conception: A Cross-Sectional Study. J Fertil In Vitro IVF Worldw Reprod Med Genet Stem Cell Biol 4:174. doi:10.4172/2375-4508.1000174
Copyright: © 2016 Dooley W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objective: To investigate the difference in perinatal and delivery outcomes in multiple pregnancies, depending on mode of conception.

Design: An observational cross sectional study.

Setting: Homerton University Hospital NHS Foundation Trust, a University Hospital in London. Sample: All multiple pregnancies delivered at the hospital between the inclusive years 2009-2012 were reviewed with a total of 341 pregnancies included.

Methods: Maternal demographics and perinatal outcomes including mortality rates, were collected on all participants.

Main outcome measures: Maternal demographics including age and length of postnatal hospital stay, pregnancy outcomes including mode of delivery, and perinatal outcomes including mortality rates.

Results: Women who conceived naturally were significantly younger (30.42 ± 5.98 years) than those conceived through assisted treatment (34.24 ± 5.73 years; p<0.05). Babies conceived through assisted treatment were born at a significantly lower gestational age (33.81 ± 4.05 weeks) than those conceived spontaneously (34.81 ± 3.55 weeks; p<0.05). The average birth weight was significantly lower in those conceived by assisted treatment as compared to those conceived naturally. More naturally conceiving women delivered by spontaneous vaginal delivery (23.9%) as compared to those conceived by assisted treatment (9.2%, p<0.05).

Conclusions: Comparable perinatal mortality rates are seen between twins conceived naturally and those conceived by assisted reproductive technology; however significantly lower gestational age, birth weight and vaginal delivery rates were seen in pregnancies conceived by assisted treatment.

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