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Journal of Bioengineering & Biomedical Science

ISSN: 2155-9538

Open Access

A Computational Approach for Identifying the Impact of Pharmacogenomics in Regulatory Networks to Understand Disease Pathology

Abstract

Harishchander A

In the current era of post genomics, there exist a varity of computational methodologies to understand the nature of disease pathology like RegNetworks, DisgiNet, pharmGkb, pharmacomiR and etc. In most of these computational methodologies either a seed pairing approach or a base pair complement is being followed. Hence there exists a gap in understanding the nature of disease pathology in a holistic view point. In this manuscript we combine the approach of seed pairing and graph theory to illustrate the impact of Pharmacogenomics in Regulatory Networks to understand disease Pathology.

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Citations: 307

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