A Cross-Sectional, Clinico-Mycological Research Study of Prevalence, Aetiology, Speciation and Sensitivity of Superficial Fungal Infection in Indian PatientsCRV Narasimhalu1*, Kalyani M2 and Somendar S3
- *Corresponding Author:
- CRV Narasimhalu
Department of Dermatology
Saveetha Medical College
Saveetha University Kancheepuram
Tamil Nadu 602-105, India
E-mail: [email protected]
Received date: October 19, 2015; Accepted date: January 18, 2016; published date: January 22, 2016
Citation: Narasimhalu CRV, M Kalyani, Somendar S (2016) A Cross-Sectional, Clinico-Mycological Research Study of Prevalence, Aetiology, Speciation and Sensitivity of Superficial Fungal Infection in Indian Patients. J Clin Exp Dermatol Res 7:324. doi: 10.4172/2155-9554.1000324
Copyright: © 2016 Narasimhalu CRV, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Skin is a mechanically protective layer as well as cosmetically significant anatomical structure. The superficial cutaneous fungal infections involve its outer most covering including appendages like hair and nails. This the most common causes of skin disease in many tropical countries. Objectives: To study the prevalence, aetiology, speciation and sensitivity of superficial fungal infections. Materials and Methods: The study was conducted on 100 clinically diagnosed cases of Superficial Fungal Infection attending the Dermatology OPD for a period of 6 months. Detailed history was taken in relation to age, sex, duration of illness, personal history, recurrent infections etc. Clinical examination of lesion included number, types of lesions, scaling, presence of crusts or pustules, scarring, black dot appearances, hair lusture etc. Samples like skin scrapings, hair stubs, nail clippings and pus were collected for KOH study and fungal culture. Results: Dermatophyte infection mostly Tinea corporis is found to be more in male in 20-30 years age group of population. Covered part of the body is affected more and commonly hygiene plays a major part of its occurrence. KOH positivity is found in 68% and culture positivity in 88.2% of the clinically diagnosed cases with Trichophyton species as the commonest. Fluconazole and Clotrimazole found to be highly sensitive ; Ketoconazole fount to be partially sensitive with 65% . Conclusion: Dermatophytes were the commonest mycological isolate with Trichophyton rubrum as the common infecting species. Young male preponderance with involvement of covered areas of the body of both skilled and unskilled workers. This can be prevented by a meticulous personal hygiene. Fluconazole and Clotrimazole found to be highly sensitive.