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ISSN: 2157-7633

Journal of Stem Cell Research & Therapy
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Research Article

A Forecast of Targeting Leukemia Stem Cells by Nanomedicine

Xiangwei Huang1,2, Xunlei Kang3* and Meng Zhao1,2,4,*

1The Third Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, China

2Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, China

3Department of Medicine, University of Missouri School of Medicine, USA

4Department of Pathophysiology, Sun Yat-Sen University, China

*Corresponding Authors:
Dr. Meng Zhao
The Third Affiliated Hospital, Zhongshan School of Medicine
Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education
Department of Pathophysiology, Zhongshan School of Medicine
Sun Yat-Sen University, Guangzhou, China
Tel: +86 20 8411 2828
E-mail: [email protected]
 
Prof. Xunlei Kang
Department of Medicine, University of Missouri School of Medicine
Columbia, MO, USA
Tel: +1 573-882-1566
E-mail: [email protected]

Received date: April 01, 2017; Accepted date: April 28, 2017; Published date: May 08, 2017

Citation: Huang X, Kang X, Zhao M (2017) A Forecast of Targeting Leukemia Stem Cells by Nanomedicine. J Stem Cell Res Ther 7:385. doi: 10.4172/2157-7633.1000385

Copyright: © 2017 Huang X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Leukemia Stem Cells (LSCs) are a subpopulation of leukemic cells that display characteristics of self-renewal, differentiation and tumor-initiating capacity. They are also thought to be responsible for Chemoradiotherapy resistance and the recurrence of leukemia. Recently, Nanomedicine has been widely used for cancer treatments with improved targeting efficiency and reduced side effects. In this review, we have summarized the studies of LSCs identification and therapeutic strategies with a commentary on recently developed cancer stem cell and LSCs targeting strategies by Nanomedicine.

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