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ISSN: 2572-4916

Journal of Bone Research
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Letter to Editor

A General View on Bone Marrow Research

Tejinde Gaurey*

Assistant Professor, Department of Haematology, University of California, USA

*Corresponding Author:
Tejinde Gaurey
Department of Haematology
University of California
Campus Box 5120, Normal, Il 61761, USA
Tel: 309-438-1875
Fax: 309-438-5559
E-mail: [email protected]

Received June 26, 2013; Accepted July 29, 2013; Published August 01, 2013

Citation: Gaurey T (2013) A General View on Bone Marrow Research. J Bone Marrow Res 1:129. doi:10.4172/2329-8820.1000129

Copyright: © 2013 Gaurey T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The hyper cellular marrow of CML shows pan myelosis and a virtual absence of adipocytes. There is granulocytic and/or megakaryocytic proliferation, eosinophilia and basophilia, occasionally with pseudo- Gaucher / sea-blue histiocytes and fibrosis. Past studies divided CML into two histological subtypes: a commoner granulocytic variant (~83%) showing unilinear granulopoietic hyperplasia, and a bilinear megakaryocytic type (~41%) additionally showing megakaryocytic hyperplasia, altered topology and pleomorphism with ineffective diminished erythropoiesis and grade 2-4 reticulin

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