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A Large Esophageal Granular Cell Tumor with Review of Literature | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Case Report

A Large Esophageal Granular Cell Tumor with Review of Literature

Jeff F Wang1, Susan Repertinger-Fisher1, Sumeet K. Mittal2 and Caishu Deng1*

1Department of Pathology, Creighton University Medical Center, USA

2Department of Surgery, Creighton University Medical Center, USA

*Corresponding Author:
Dr. Caishu Deng, MD
Department of Pathology
Creighton University, 601 N
30th Street, Omaha, NE 68131, USA
Tel: (402) 449 4633
Fax: (402) 280 5247
E-mail: [email protected]

Received Date: April 07, 2011; Accepted Date: November 01, 2011; Published Date: November 03, 2011

Citation: Wang JF, Repertinger-Fisher S, Mittal SK, Deng C (2011) A Large Esophageal Granular Cell Tumor with Review of Literature. J Cancer Sci Ther 3: 213-215. doi: 10.4172/1948-5956.1000091

Copyright: © 2011 Wang JF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Granular cell tumor (GCT) is an uncommon entity which occurs in all organs and tissues and is most frequently found in the tongue and skin. Within the gastrointestinal system, granular cell tumor occurs most frequently within the esophagus. The clinical presentation and imaging features of esophageal GCT overlap with leiomyoma in many aspects, making it difficult to separate these entities on a purely clinical basis. Therefore, the definitive diagnosis of granular cell tumor relies upon pathological examination. GCT of the esophagus is benign and surgical excision is usually curative. Here we report a case of a large, submucosal GCT of the distal esophagus, mimicking leiomyoma in clinical presentation and on esophagogastroduodenoscopy (EGD) imaging. Surgical resection resulted in apparent cure, with no recurrence after 3 years of follow-up. Pathologic examination of the lesion showed a typical granular cell tumor.


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