alexa A Lymphatically Metastasized Perivascular Epithelioid Cell Tumor from the Uterus | OMICS International | Abstract
ISSN: 2161-0932

Gynecology & Obstetrics
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Case Report

A Lymphatically Metastasized Perivascular Epithelioid Cell Tumor from the Uterus

Klerkx WM1*, Sie-Go DMDS2, Daan NMP1, Witteveen PO3 and Verheijen RHM1

1Department of Gynecology and Obstetrics, University Medical Center Utrecht, Netherlands

2Department of Pathology, University Medical Center Utrecht, The Netherlands

3Department of Medical Oncology, University Medical Center Utrecht, Netherlands

*Corresponding Author:
Klerkx WM
Department of Gynaecology and Obstetrics
University Medical Center Utrecht
Heidelberglaan 100
3584 CX Utrecht, The Netherlands
Tel: +31-88-7555555
Fax: +31-88-7555507
E-mail: [email protected]

Received Date: August 23, 2013; Accepted Date: September 13, 2013; Published Date: September 18, 2013

Citation: Klerkx WM, Sie-Go DMDS, Daan NMP, Witteveen PO, Verheijen RHM (2013) A Lymphatically Metastasized Perivascular Epithelioid Cell Tumor from the Uterus. Gynecol Obstet 3:170. doi: 10.4172/2161-0932.1000170

Copyright: © 2013 Klerkx WM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Perivascular Epithelioid tumor (PEComa) is a rare malignancy which may occur at various anatomic sites. A case is described of PEComa in multiple lymph nodes in a 34 year old woman with adenocarcinoma of the cervix. Laparoscopic pelvic lymph node dissection revealed perivascular epithelioid tumor cells in 15/34 pelvic lymph nodes and no sign of the adenocarcinoma. At subsequent radical hysterectomy the primary tumor was found in the uterus, besides the stage IB1 adenocarcinoma of the cervix. No adjuvant treatment was given and the patient remained well, until the time of evaluation, 20 months after diagnosis.

A systematic review is performed about gynecological PEComa with lymphatic involvement concerning diagnosis, treatment and overall survival.


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