A Mini Review of Candida Species in Hospital Infection: Epidemiology,Virulence Factor and Drugs Resistance and Prophylaxis
Janaina de Cássia Orlandi Sardi*, Nayla de Souza Pitangui, Fernanda Patrícia Gullo and Ana Marisa Fusco Almeida e Maria José Soares Mendes Giannini
Departme nt of Clinical Analysis, Clinical Mycology Laboratory, Faculty of Pharmaceutical Sciences, UNESP - Univ Estadual Paulista, Araraquara, SP 14801- 902, Brazil
- *Corresponding Author:
- Janaina de Cassia Orlandi Sardi
Faculty of Pharmaceutical Sciences of Department of Clinical Analysis
Laboratory of Clinical Mycology, Univ Paulista (UNESP), Brazil
Tel: +55 16 3301 5716
E-mail: [email protected]
Received Date: June 20, 2013; Accepted Date: August 26, 2013; Published Date: September 01, 2013
Citation: de Cássia Orlandi Sardi J, de Souza Pitangui N, Gullo FP, e Maria José Soares Mendes Giannini AMFA (2013) A Mini Review of Candida Species in Hospital Infection: Epidemiology, Virulence Factor and Drugs Resistance and Prophylaxis. Trop Med Surg 1:141 doi: 10.4172/2329-9088.1000141
Copyright: © 2013 de Cássia Orlandi Sardi J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The introduction of more efficient diagnostic methods, new techniques in surgery and transplantation, antibiotics and chemotherapeutics more potent and novel materials for prostheses, catheters and probes significantly increased the life expectancy and quality of life of critically ill patients, on the other hand, hospital-acquired infections emerged as important iatrogenic complications. Invasive infections are a growing problem in public health hospitals in Brazil and worldwide. Among the various etiological agents found in the hospital environment, the genus Candida has been the third most frequently isolated pathogen. In general, invasive fungal infections are associated with high morbidity and mortality, difficulties in diagnosis, antimicrobial resistance, length of hospital stay and increased hospital costs. This mini review of the literature describes about epidemiology of hospital infection of Candida species, as well as its virulence factors and drugs resistance.