A Mini-Review: MicroRNA in Tendon InjuriesJia Guo1, Jin-fang Zhang1-3, Gang Li1-5, Kai-ming Chan1,2,4,5*`
- *Corresponding Author:
- Kai-Ming Chan
Department of Orthopaedics and Traumatology
The Chinese University of Hong Kong
Prince of Wales Hospital, Hong Kong SAR, PR China
E-mail: [email protected]
Received date: July 28, 2015; Accepted date: September 07, 2015; Published date: September 09, 2015
Citation: Guo J, Zhang JF, Li G, Chan KM (2015) A Mini-Review: MicroRNA in Tendon Injuries. J Stem Cell Res Ther 5:303. doi:10.4172/2157-7633.1000303
Copyright: © 2015 Guo J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Tendon injury is a difficult clinical problem. Till now, the basic cell biology of tendons is still not fully understood and the management of tendon injury poses a considerable challenge for clinicians. Endogenous microRNAs are short noncoding RNA molecules which can negatively regulate gene expression at the post-transcriptional level. The regulatory role of miRNA has well been studied in many diseases, however the significance of miRNAs in tendon injuries remains elusive. This review summarized the miRNAs related to the pathogenesis of tendinopathy and tendon injuries and highlighted their clinical potential, which may bring new insights into developing a novel advanced strategy toward tendon injury treatment.