alexa A New Phenyl Tetraglucoside and Phenolic Diglucoside fr
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

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Research Article

A New Phenyl Tetraglucoside and Phenolic Diglucoside from Picrorhiza kurroa Royle ex Benth

Naresh Fandon* and Surendra Kr Sharma

Department of Pharmacognosy, Faculty of Medical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001, India

*Corresponding Author:
Fandon N
Department of Pharmacognosy, Faculty of Medical Sciences
Guru Jambheshwar University of Science and Technology, Hisar-125001, India
E-mail: [email protected]

Received date: May 25, 2017; Accepted date: June 05, 2017; Published date: June 10, 2017

Citation: Fandon N, Sharma SK (2017) A New Phenyl Tetrasglucoside and Phenolic Diglucoside from Picrorhiza kurroa Royle ex Benth. Nat Prod Chem Res 5:274. doi:10.4172/2329-6836.1000274

Copyright: © 2017 Fandon N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Context

Picrorhiza kurroa Royle ex Benth (Scrophulariacae) is a small perennial herb distributed in the alpineHimalayan tract and in some tropical parts of India. The production of two compounds Phenyl tetraglucoside and Phenolic diglucoside bioactive in Picrorrhiza kurroa. It may suggest that it is containing an interesting bioactive compound.

Aim

This research aimed to characterize the new phenyl tetraglucoside and phenolic diglucoside compounds in Picrorrhiza species (kurroa sp.) found on the Himalayan and some tropical parts of India.

Subjects and Methods

Isolation of bioactive compounds through total methanol extracts. It has been done with spectral studies using thin layer chromatography. The structures of both compounds were elucidated on the basis of UV, IR, Nuclear Magnetic Resonance (H1 and C13 NMR) and Mass spectroscopic studies.

Results

Elucidation showed that compounds found as a new Phenyl tetraglucoside, namely, as 3-methoxy-4 hydroxyphenyl-n-butanyl-o-α-L-glucopyranosyl-(4a→1b)-α-L glucopyranosyl-(4b→1c)-α-L-glucopyranosyl-(4c→1d)-α-L-glucopyranosyl-4d-(3'-methoxy-4-hydroxyphenyl)-n-pent-7', 9'- dien-11'-oate, Phenolic diglucoside and vanillyl glucoside.

Conclusion

Results of this study suggest that a Picrorhiza kurroa species is a potential source of various active compounds.

Keywords

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