alexa A Novel Approach to Formulate and Optimize Orally Disintegrating Tablets of Bambuterol Hydrochloride | OMICS International | Abstract
ISSN : 2153-2435

Pharmaceutica Analytica Acta
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

A Novel Approach to Formulate and Optimize Orally Disintegrating Tablets of Bambuterol Hydrochloride

Liandong Hu*, Deliang Gu, Qiaofeng Hu, Hailei Zhang and Xun Yang

College of Pharmacy, Hebei University and Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China

*Corresponding Author:
Liandong Hu
College of Pharmacy
Hebei University and Key Laboratory of Pharmaceutical
Quality Control of Hebei Province, Hebei University
Baoding, 071002, China
Tel: +86-312-5971107
Fax: +86-312-5971107
E-mail: [email protected]

Received date: January 14, 2013; Accepted date: March 14, 2013; Published date: March 24, 2013

Citation:Hu L, Gu D, Hu Q, Zhang H, Yang X (2013) A Novel Approach to Formulate and Optimize Orally Disintegrating Tablets of Bambuterol Hydrochloride. Pharmaceut Anal Acta 4:216. doi: 10.4172/2153-2435.1000216

Copyright: © 2013 Hu L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The aim of this article was to choose the optimal ingredients for oral disintegrating tablets of bambuterol hydrochloride (BBH) and use a novel approach to measure disintegration time. The disintegration time measured by a new approach was compared with disintegration time measured in oral cavity and conventional disintegration test. The result shows that the new apparatus is suitable for measuring the disintegration time. The effect of ingredients (diluents, disintegrants and adhesives) on the characteristics of the tablets was investigated. The orally disintegrating tablets of BBH were prepared by wet granulation. The results showed that the optimum proportion was 10 mg BBH, 100 mg lactose, 80 mg MCC, 10 mg crospovidone (PVPP), 2 mg aspartame, 2 mg DL-malic acid. The orally disintegrating tablet disintegrated rapidly, tasted good and could be taken convenient.

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version