A Novel Approach to the Treatment of Sebaceous Hyperplasia and Post- Procedural Purpura with Pulsed-Dye Laser
- *Corresponding Author:
- Paul M. Graham
Department of Dermatology
5333 McAuley Dr # 5011
Ypsilanti, MI 48197
E-mail: [email protected]
Received date: 21 June, 2016; Accepted date: 12 July, 2016; Published date: 18 July, 2016
Citation: Graham PM, Eubanks SW (2016) A Novel Approach to the Treatment of Sebaceous Hyperplasia and Post-Procedural Purpura with Pulsed-Dye Laser. J Clin Exp Dermatol Res 7:363. doi:10.4172/2155-9554.1000363
Copyright: © 2016 Graham PM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Sebaceous hyperplasia is a benign but clinically and cosmetically unappealing lesion. Historical treatments include cauterization, cryotherapy, chemical ablation, and surgical removal, all of which increase the risk for permanent post-operative adverse effects. The pulsed-dye laser (PDL) offers a safe and effective approach to the treatment of sebaceous hyperplasia in Fitzpatrick skin types I-III, but purpura was an unacceptable trade off of this treatment. We describe a subsequent follow-up treatment aimed at reducing the resulting post-PDL purpura.
Methods: Our report presents 5 patients (Fitzpatrick II-III) treated with PDL (595 nm, 5 mm spot, 20 J/cm2, 3 ms) for sebaceous hyperplasia with subsequent follow-up treatment, 24-hours later, with the same PDL (595 nm, 7 mm spot, 9 J/cm2, 6 ms, DCD 30/20) aimed at improving the post-operative purpura.
Results: Sebaceous hyperplasia and resulting purpura improved after a single combination treatment session with both high and moderate-fluence PDL. Purpura is required for effective treatment of sebaceous hyperplasia, but is subsequently treated with moderate-fluence PDL 24-hours later, offering complete resolution of post-PDL purpura within 72 hours.
Conclusion: Treatment of sebaceous hyperplasia with PDL offers a safe and effective treatment modality aimed at the underlying vasculature associated with the sebaceous gland. The high-fluence and short pulse duration required to remove the sebaceous hyperplasia often leads to the development of purpura. This post-PDL purpura is successfully treated with moderate-fluence PDL with resolution within 72 hours. In the future, we believe that many other conditions requiring high-fluence PDL that leads to purpura may also be treated with a subsequent lower dose treatment to remove any laser induced purpura.