A Novel Sensitive Fluorescent Coumarin-Based Chemosensor for Detection of Copper Ion
- *Corresponding Author:
- Ahmadreza Bekhradnia
Pharmaceutical Sciences Research Center
Department of Medicinal Chemistry
Mazandaran University of Medical Sciences, Sari, Iran
Tel: (0151) 3262679
Email: [email protected]
Received date: January 21, 2016;Accepted date: February 02, 2016; Published date: February 05, 2016
Citation: Bekhradnia A, Ghanbarimasir Z (2016) A Novel Sensitive Fluorescent Coumarin-Based Chemosensor for Detection of Copper Ion. Pharm Anal Acta 7:461. doi:10.4172/2153-2435.1000461
Copyright: © 2016 Bekhradnia A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A sensitive fluorescent chemosensor was developed for detecting CuII through microwave irradiation by using diethylamino-3-carboxamide coumarin. This receptor was employed as fluorescent probe for CuII with selectivity over other cations in aqueous solution. The fluorescence intensity quenched when 7-diethylamino-N-[2-(dimethylamino) ethyl]-2-oxo-2H-chromene-3-carboxamide (3) used as a receptor in the presence of very low concentration of CuII with an excitation at 360 nm.