alexa A Novel Sensitive Fluorescent Coumarin-Based Chemosenso
ISSN : 2153-2435

Pharmaceutica Analytica Acta
Open Access

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Research Article

A Novel Sensitive Fluorescent Coumarin-Based Chemosensor for Detection of Copper Ion

Ahmadreza Bekhradnia1* and Zahra Ghanbarimasir2

1Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran

2Student Research Committee, Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran

*Corresponding Author:
Ahmadreza Bekhradnia
Pharmaceutical Sciences Research Center
Department of Medicinal Chemistry
Mazandaran University of Medical Sciences, Sari, Iran
Tel: (0151) 3262679
Email: [email protected]

Received date: January 21, 2016;Accepted date: February 02, 2016; Published date: February 05, 2016

Citation: Bekhradnia A, Ghanbarimasir Z (2016) A Novel Sensitive Fluorescent Coumarin-Based Chemosensor for Detection of Copper Ion. Pharm Anal Acta 7:461. doi:10.4172/2153-2435.1000461

Copyright: © 2016 Bekhradnia A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

A sensitive fluorescent chemosensor was developed for detecting CuII through microwave irradiation by using diethylamino-3-carboxamide coumarin. This receptor was employed as fluorescent probe for CuII with selectivity over other cations in aqueous solution. The fluorescence intensity quenched when 7-diethylamino-N-[2-(dimethylamino) ethyl]-2-oxo-2H-chromene-3-carboxamide (3) used as a receptor in the presence of very low concentration of CuII with an excitation at 360 nm.

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