alexa A Nutritional Supplement Formulated with Peptides, Lipids, Collagen and Hyaluronic Acid Optimizes Key Aspects of Physical Appearance in Nails, Hair and Skin | Abstract
ISSN: 2155-9600

Journal of Nutrition & Food Sciences
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Research Article

A Nutritional Supplement Formulated with Peptides, Lipids, Collagen and Hyaluronic Acid Optimizes Key Aspects of Physical Appearance in Nails, Hair and Skin

Michelle R. Yagoda MD1* and Eugene H Gans PhD2

1Facial Plastic Surgeon, Private Practice, and Associate Attending Surgeon, Manhattan Eye, Ear and Throat Hospital, Lenox Hill Hospital, North Shore-LIJ Health System, New York, USA

2President and Pharmaceutical Consultant, Hastings Senior Associates, New York, USA

*Corresponding Author:
Michelle R. Yagoda MD
1025 Fifth Avenue, New York 10028, USA
Tel: 212-434-1210
Fax: 212-535-8155
E-mail: [email protected]

Received date: March 05, 2014; Accepted date: April 26, 2014; Published date: April 28, 2014

Citation: Yagoda MR, Gans EH (2012) A Nutritional Supplement Formulated with Peptides, Lipids, Collagen and Hyaluronic Acid Optimizes Key Aspects of Physical Appearance in Nails, Hair and Skin. J Nutr Food Sci S5:002. doi: 10.4172/2155-9600.S5-002

Copyright: © 2014 Yagoda MR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Symptoms of dryness in the skin, hair and nails increase with age, and with certain medical, environmental and physiologic conditions—affecting a significant portion of the population. Topical therapies can be limited by the skin’s inherent barrier function, and simply ingesting a balanced and varied diet may not be enough to prevent nutritional deficiencies. The authors describe two double-blinded, placebo vs. control clinical studies, including one 60-week cross-over study, on the effect of a nutritional supplement formulation on hair, skin, and nails. The supplement formulation, that contained peptides, lipids, hyaluronic acid, and collagen as its active ingredients, was given to participants in 20- gram oral doses once daily, and the results show the magnitude of its effectiveness. The data showed statistically significant improvement in nail cracking, nail brittleness, hair dullness, hair dryness, and nail softness after 8 weeks. There was a significant decrease in skin dryness over the same period. The crossover study showed that those receiving the supplement had statistically significant benefits for as long as 52 weeks, then when the cross-over was performed and the supplement was withdrawn, there was a significant decline in benefits. Of those subjects with more severe symptoms at the outset, 95% saw significant improvement in hair dryness and dullness, 85% in nail splitting and peeling, and 65% in nail hardness. The authors conclude that this nutritional supplementation should be considered as an important, effective and perhaps necessary component of complete hair, nail and skin care regimens.

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