alexa A Proposal to Reduce Congenital Cerebral Palsy | OMICS International | Abstract
ISSN: 2157-7420

Journal of Health & Medical Informatics
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Review Article

A Proposal to Reduce Congenital Cerebral Palsy

Kazuo Maeda*

Department of Obstetrics and Gynecology (Honorary Professor), Tottori University Medical School, Yonago, Japan

*Corresponding Author:
Kazuo Maeda
Department of Obstetrics and Gynecology (Honorary Professor)
Tottori University Medical School, 3-125, NadamachiYonago, japan
Tel: +81-859-22-6856
Fax: +81-859-22-6856
E-mail: [email protected]

Received date: October 14, 2013; Accepted date: October 15, 2013; Published date: October 19, 2013

Citation: Maeda K (2013) A Proposal to Reduce Congenital Cerebral Palsy. J Health Med Informat 4:135. doi: 10.4172/2157-7420.1000135

Copyright: © 2013 Maeda K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Aims: To clarify the feasibility to arrest preterm labor to prevent the periventricular leukomalacia (PVL) and Cerebral Palsy (CP) by the study on the developing mechanism of labor contractions.

Rational: Fetal periventricular echo density (PVE) precedes preterm neonatal PVL and CP in 18% of preterm fetuses whose PVE persisted until preterm births. Since no treatment of neonatal PVE appeared immediately after preterm birth was established, another strategy is proposed to prevent preterm neonatal PVE to cease preterm labor until the full term delivery, because no CP developed in full term delivery in our report. Recently, we studied the positive feed-back loop of uterine contraction to the brain by nerves between the uterus and hypothalamus, developing regular labor contractions.

Proposal: The suppression of the nerves of positive feed-back loop by anesthesia or analgesia is our proposal to cease preterm labor until the full term delivery, where no CP was reported, i.e. the CP, corresponding to 0.2% of total births, will be reduced.

Conclusion: Regular preterm labor contractions will be ceased by the paralysis of nerves in the positive feed-back loop between the uterus and hypothalamus and the full-term delivery prevents CP, due to disappeared PVE in the neonates born in full term delivery. Clinical feasibility should be investigated in further studies.


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