A Rare Case of Ovarian Sertoli-Leydig Cell Tumor in Postmenopausal Woman Presenting with Alopecia
Department of Physiology, Nkpsalve Institute of Medical Science, India
- *Corresponding Author:
- Anagha Sahasrabuddhe
Assistant Professor, Department of Physiology
Nkpsalve Institute of Medical Science, India
E-mail: [email protected]
Received date: February 29, 2016; Accepted date: May 19, 2016; Published date: May 26, 2016
Citation: Sahasrabuddhe A (2016) A Rare Case of Ovarian Sertoli-Leydig Cell Tumor in Postmenopausal Woman Presenting with Alopecia. Endocrinol Metab Syndr 5:234. doi:10.4172/2161-1017.1000234
Copyright: © 2016 Sahasrabuddhe A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Mild hirsutism and alopecia in postmenopausal women can be a normal physiological response. Sex cord stromal tumors of ovary account for approximately 5-8% of all ovarian tumors. When hirsutism is accompanied by signs of virilization such as severe balding, deepening of voice or clitoromegaly, an underlying androgen-secreting tumor, that may be malignant must be ruled out. We report a rare case of 46 year old female with premature menopause and symptom of hair loss. She had high testosterone levels and left ovary mass. As Cushing syndromes and late onset congenital adrenal hyperplasia were ruled out, an ovarian source of androgen was suspected. She underwent hysterectomy with bilateral salpingo-oophorectomy. A diagnosis of left ovarian sex-cord stromal tumor favoring Sertoli-Leydig cell tumor was confirmed. We report this case for its rare nature and atypical presentation.