A Rare Presentation of Pemphigus Erythematosus as Pustules
- *Corresponding Author:
- Gui-Lan Yang
Associate Professor, Department of Dermatology
Lanzhou General Hospital of Lanzhou Military Area Command
Lanzhou 730050, China
E-mail: [email protected]
Received date: April 25, 2014; Accepted date: June 07, 2014; Published date: June 14, 2014
Citation: Yang GL, Zhao M, Wang JF, Xiao H, Pan Z (2014) A Rare Presentation of Pemphigus Erythematosus as Pustules. J Clin Exp Dermatol Res 5:222. doi:10.4172/2155-9554.1000222
Copyright: © 2014 Gui-Lan Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Pemphigus erythematosus (PE) is an autoimmune blistering disease that is characterized by erythema and blisters, but rarely pustules, on the upper torso, face, and scalp. A 37-year-old woman presented with a 20 day history of intense pruritus as well as multiple papules and pustules on the trunk and face. Initially, the disease was misdiagnosed as impetigo due to the presence of pustules, nontypical lesions, and pathology results. Histopathology of new bullas showed epidermal hyperkeratosis, blistering and typical acantholysis, and the presence of diffuse inflammatory cells. Direct immunofluorescence showed intraepidermal, intercellular deposition of IgG autoantibodies. A diagnosis of pemphigus erythematosus was made. Systemic steroid therapy was effective in controlling the disease. To the best of our knowledge, this is the first case report on pemphigus erythematosus presenting with pustules.