A Review of Arterial Stiffness and HIV Infection in Adult Africans
- *Corresponding Author:
- Dr. Kofoworola Olajire Awotedu
Walter Sisulu University, Mthatha, Eastern Cape
E-mail: [email protected], [email protected]
Received date April 12, 2016; Accepted date April 29, 2016; Published date May 09, 2016
Citation: Awotedu OK, Iputo J (2016) A Review of Arterial Stiffness and HIV Infection in Adult Africans. J Hypertens 5:221. doi:10.4172/2167-1095.1000221
Copyright: ©2016 Awotedu KO, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Aim: To review the impact of the human immunodeficiency virus and antiretroviral therapy on the vasculature.
Objectives: This review seeks to identify the burden which the human immunodeficiency virus and antiretroviral therapy have on the vasculature.
Method: Medline/PubMed and Google scholar were searched. There were over 100 publications reviewed. Some people who worked in similar fields were also contacted. The present review summarized current understanding of Human immunodeficiency virus, antiretroviral therapy and effect on the vasculature such as arterial stiffness. Atherosclerosis, endothelial dysfunction, the strengths and weaknesses of current testing strategies, and their potential applications in clinical research and patient care. The association of inflammatory biomarkers, blood pressure and ageing with arterial stiffness were also reviewed.
Conclusion: Available literature shows that HIV and antiretroviral agents have a great impact on the vasculature and its progression.