alexa A Review of the Detection of Amino Acids in Tumor Tissue with 1H Magnetic Resonance Spectroscopy in vivo
ISSN: 2155-9937

Journal of Molecular Imaging & Dynamics
Open Access

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Review Article

A Review of the Detection of Amino Acids in Tumor Tissue with 1H Magnetic Resonance Spectroscopy in vivo

Dorota Bartusik1*, David Aebisher2 and BoguslawTomanek1,3,4

1Cross Cancer Institute, Department of Medical Physics, Edmonton, Alberta, Canada

2Shorter University, Natural Sciences Department, Georgia, USA

3University of Calgary, Department of Clinical Neurosciences and Radiology, Calgary, Alberta, Canada

4Polish Academy of Sciences, Institute of Nuclear Physics, Kraków, Poland

*Corresponding Author:
Dorota Bartusik
Cross Cancer Institute, Department of Medical Physics
11560 University Ave, Edmonton
T6G 1Z2 Alberta, Canada
E-mail: [email protected]

Received date: June 17, 2013; Accepted date: August 12, 2013; Published date: August 14, 2013

Citation: Bartusik D, Aebisher D, Tomanek B (2013) A Review of the Detection of Amino Acids in Tumor Tissue with 1H Magnetic Resonance Spectroscopy in vivo. J Mol Imaging Dynam 3:112. doi:10.4172/2155-9937.1000112

Copyright: © 2013 Bartusik D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The biochemical components of tumor tissue are generally different from normal tissue. A variety of techniques, including of magnetic resonance (MR) are used to study metabolic compounds and their associated biochemical pathways in tumor tissue in vivo. This review provides an overview of applications of MR spectroscopy (MRS) to the identification of biochemical characteristics, e.g. amino acids present during tumor growth. MRS is a technology that allows spatial localization and structural studies of amino acids and is gaining in use as a diagnostic tool. This review is intended to provide information about potential applications of MRS to non-invasive probing of the underlying amino acid biochemistry in tumors. Articles discussed in this review are classified into the following categories:hardware for 1H MRS, acquisition methods, software, and 1H MRS of amino acids in tumor tissue in vivo.


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