alexa A Review on 4, 5-Imidazoledicarboxylic Acid: Their Chem
ISSN: 2329-6798

Modern Chemistry & Applications
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Review Article

A Review on 4, 5-Imidazoledicarboxylic Acid: Their Chemistry and Coordination Potentials

Worku Batu Dirersa*

Department of Chemistry, Ambo University, Oromia, Ethiopia

*Corresponding Author:
Worku Batu Dirersa
Department of Chemistry
Ambo University, Oromia, Ethiopia
Tel: +251920231043
E-mail: [email protected]

Received Date: June 13, 2016 Accepted Date: June 21, 2016 Published Date: June 23, 2017

Citation: Dirersa WB (2017) A Review on 4, 5-Imidazoledicarboxylic Acid: Their Chemistry and Coordination Potentials. Mod Chem appl 5: 222. doi: 10.4172/2329- 6798.1000222

Copyright: © 2017 Dirersa WB. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



As part of heterocyclic imidazole interest to explore new receptors for anion; 4,5-imidazoledicarboxylic acid and their derivatives have great roles in coordination chemistry. This review, was also update the application and behaviour of 4,5-imidazoledicarboxylic acid (H3IMDC) as a potential motif for coordination compound in supramolecular structure activity. H3IMDC contains one imidazole NH and two COOH protons which could be donated for hydrogen bonding to the anions. Due to the electronic properties of carboxyl group oxygens, coordination to metal ions can occur in different modes. In situ ligand synthesis is of growing interest as a new approach for the synthesis of coordination polymers. The main reason for interesting of 4,5-imidazoledicarboxylic acid (H3IMDC) and its derivatives in coordination polymers of metal-organic framework is because it has six potential donor atoms: two imidazole nitrogens and four carboxylate oxygen atoms, and can remove one to three hydrogen atoms forming H3-nIMDCn- (n=1,2 or 3) species. The six donors may show various coordination modes and construct beautiful structures. In present review, the chemistry of 4,5-imidazoledicarboxylic acid and its coordination potential in coordination and supramolecular chemistry, which are uses as input for medicinal and drug synthesis, pharmacological actions and as biological activity; where reviewed based on the coordination potentials of imidazole derived heterocyclic molecules in metal-organic frameworks.


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