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ISSN: 2167-0412

Medicinal & Aromatic Plants
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Review Article

A Review on Therapeutic Potential of Piper nigrum L. (Black Pepper): The King of Spices

Zoheir A Damanhouri1* and Aftab Ahmad2
1Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
2Health Information Technology Department, Jeddah Community College, King Abdulaziz University, Jeddah-21589, Kingdom of Saudi Arabia
Corresponding Author : Zoheir A Damanhouri
Department of Pharmacology
Faculty of Medicine
King Abdulaziz University
P.O.Box 80205
Jeddah 21589
Saudi Arabia
Tel: +966507770848
E-mail: [email protected]
Received May 02, 2014; Accepted July 30, 2014; Published August 04, 2014
Citation: Damanhouri ZA, Ahmad A (2014) A Review on Therapeutic Potential of Piper nigrum L. (Black Pepper): The King of Spices. Med Aromat Plants 3:161. doi:10.4172/2167-0412.1000161
Copyright: 2014 Damanhouri ZA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Medicinal plants are very popular in different traditional systems of medicines due to their diverse pharmacological potentials and lesser side effects in biological systems. Piper nigrum L. (Family Piperaceae) is a well known spice considered as ‘‘The King of spices’’ among various spices. It contains a pungent alkaloid ‘‘piperine’’ which is known to possess many pharmacological actions. Piperine increases bioavailability of many drugs and nutrients by inhibiting various metabolising enzymes. Piper nigrum L and its active constituent ‘’Piperine’’exhibits diverse pharmacological activities like antihypertensive, antiplatelet, antioxidant, antitumor, anti-asthmatics, analgesic, anti-inflammatory, anti-diarrheal, antispasmodic, antidepressants, immunomodulatory, anticonvulsant, anti-thyroids, antibacterial, antifungal, hepato-protective, insecticidal and larvicidal activities etc. The current review article is aimed to provide an updated literature review on recent advancement of pharmacognosy, chemistry and pharmacological activities of Piper nigrum L.

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