alexa A Review on Underlying Differences in the Prevalence of Metabolic Syndrome in the Middle East, Europe and North America
ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
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Review Article

A Review on Underlying Differences in the Prevalence of Metabolic Syndrome in the Middle East, Europe and North America

Mohsen Nematy1, Farnaz Ahmadpour1, Zahra Behnam Rassouli1, Hosein Mohaddes Ardabili1 and Mohsen Azimi-Nezhad2,3*

1Department of Nutrition, School of Medicine, Biochemistry and Nutrition, Endoscopic & Minimally Invasive Surgery, and Cancer Research Centers, Mashhad University of Medical Sciences (MUMS) Mashhad, Iran

2Department of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences (MUMS) Mashhad, Iran

3Research Unit "Gene-Environment Interactions in Cardiovascular Pathophysiology" University of Lorraine, UMR INSERM U 1122, IGE-PCV, Nancy, France

Corresponding Author:
Mohsen Azimi-Nezhad
Department of Medical Genetics, School of Medicine
Mashhad University of Medical Sciences (MUMS) Mashhad, Iran
Tel: +985118827046
Fax: +985118827051
E-mail: [email protected]

Received Date: December 16, 2013; Accepted Date: February 17, 2014; Published Date: February 20, 2014

Citation: Nematy M , Ahmadpour F, Rassouli ZB, Ardabili HM, Azimi-Nezhad M (2014) A Review on Underlying Differences in the Prevalence of Metabolic Syndrome in the Middle East, Europe and North America. J Mol Genet Med S1:019. doi:10.4172/1747-0862.S1-019

Copyright: © 2014 Azimi-Nezhad M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Increasing burden of obesity, the metabolic syndrome (MetS), Type 2 Diabetes Mellitus (T2DM), and CardioVascular Diseases (CVD) in developing countries has created an urgent need for more researches on the various factors responsible for increasing their prevalence. Literature search was carried out using the terms obesity, insulin resistance, diabetes, dyslipidemia, physical inactivity, the metabolic syndrome, and developing countries, in order to review the criteria and risk factors of MetS and its prevalence in Middle East countries from web sites and published documents. The prevalence of the syndrome and its underlying factors was also compared between some of the Middle East and some of European and American countries. The pattern of the components of metabolic syndrome varies in the Middle East region in comparison with Europe and North America. In addition to differences of diet behaviors, the genetic factors and some of geographic dependent elements may influence the variation of metabolic syndrome architecture worldwide particularly in the Middle East region.

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